Detailed information NTG0059925

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: L897_RS02270
• Genome accession: NC_021807
• Coordinates: 432882..434234 (+)
• Length: 450 a.a.
• NCBI ID: WP_002985643.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes HSC5
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 427882..439234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L897_RS02245 (L897_02350)	-	428031..428180 (+)	150	WP_002994198.1	hypothetical protein	-
L897_RS02250 (L897_02355)	-	428575..429723 (+)	1149	WP_014635346.1	acetyl-CoA C-acyltransferase	-
L897_RS02255 (L897_02360)	-	429680..430927 (+)	1248	WP_002995606.1	AMP-binding protein	-
L897_RS02260 (L897_02365)	-	430983..432017 (+)	1035	WP_011284595.1	DUF3114 domain-containing protein	-
L897_RS02265 (L897_02370)	vicR	432179..432889 (+)	711	WP_002985645.1	response regulator YycF	Regulator
L897_RS02270 (L897_02375)	vicK	432882..434234 (+)	1353	WP_002985643.1	cell wall metabolism sensor histidine kinase VicK	Regulator
L897_RS02275 (L897_02380)	vicX	434238..435047 (+)	810	WP_002985641.1	MBL fold metallo-hydrolase	Regulator
L897_RS02280 (L897_02385)	rnc	435479..436171 (+)	693	WP_020833335.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51439.91 Da
• Isoelectric Point: 5.5556

>NTDB_id=59925 L897_RS02270 WP_002985643.1 432882..434234(+) (vicK) [Streptococcus pyogenes HSC5]
MTRDIIGNLSTFELAILILLVFVAFYFIHLAVRDYRNARIIRMMSHKIRYLINGRYTDIIDEKADIELMELSDQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLSKEEALKKNITDLLEGDTSYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLAVEMTNFTAFITSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWIEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKTDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDVD

Nucleotide

• Length: 1353 bp

>NTDB_id=59925 L897_RS02270 WP_002985643.1 432882..434234(+) (vicK) [Streptococcus pyogenes HSC5]
ATGACTAGAGATATCATTGGAAACTTATCCACATTTGAATTAGCGATCCTTATCTTACTTGTTTTTGTTGCTTTTTACTT
TATCCATCTTGCGGTGCGTGATTACCGAAATGCACGTATTATTCGGATGATGAGCCATAAAATCCGATACTTGATTAATG
GTCGCTATACTGATATAATCGACGAAAAAGCAGACATTGAGTTAATGGAGCTTTCAGACCAGTTAAATGACCTGTCAGAT
GTTTTTCGCTTGACGCATGAAAATCTTGCCCAAGAAAAAAATCGCTTGGCAAGTATTTTGGCTTATATGTCAGATGGTGT
ACTTGCTACAGACCGGTCTGGTAAAATCATCATGATTAACGAAACAGCTCGCAAGCAATTAAATTTAAGTAAAGAAGAGG
CACTAAAGAAAAACATTACAGATTTGTTAGAAGGTGATACTTCATATACCTACCGTGATTTGGTATCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGTGAGTTTGTCTCATTACGCTTGCGCTTTGCGTTGAATAGGAGAGAGAGTGG
TTTTATTTCGGGCTTGGTTGTGGTGCTCCATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTCT
CTAATGTAAGTCATGAATTAAGGACCCCTTTAACTTCGGTTAAATCCTACTTGGAGGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCAGATCTTTTAAA
CCTGTCTCGGATTGATAATCAAGTAACCCAATTAGCAGTAGAGATGACTAATTTTACTGCTTTTATAACTTCTATTTTAA
ACAGATTTGATTTGGTTAAAAATCAGCATACAGGTACAGGAAAAGTCTATGAAATTGTAAGAGATTACCCTATTACCTCT
GTCTGGATTGAAATTGATAATGATAAAATGACACAGGTTATCGAGAATATTTTGAACAATGCCATTAAGTATTCTCCAGA
TGGTGGAAAAATCACAGTCCGTATGAAAACAACAGATACCCAATTAATTATTTCCATTTCAGACCAAGGACTAGGTATCC
CTAAAACAGATTTGCCTCTTATTTTTGATCGGTTCTATCGTGTAGACAAGGCAAGAAGTCGTGCCCAAGGAGGGACCGGT
CTAGGCCTTGCCATTGCTAAAGAAATCATCAAGCAGCACCATGGCTTTATCTGGGCTAAGAGTGACTATGGTAAAGGATC
GACCTTTACTATTGTCTTGCCTTATGAAAAAGATGCAGCCATCTATGAAGAATGGGAGGAAGATGTAGACTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-162)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.947	92	0.671
micB	Streptococcus pneumoniae Cp1015	67.529	94.444	0.638