Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KFZ60_RS09270 Genome accession   NZ_CP098231
Coordinates   1938039..1938695 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain XJ34     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1933039..1943695
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KFZ60_RS09240 (KFZ60_09215) dcyD 1933918..1934904 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KFZ60_RS09245 (KFZ60_09220) tcyL 1934919..1935587 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KFZ60_RS09250 (KFZ60_09225) tcyN 1935584..1936336 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KFZ60_RS09255 (KFZ60_09230) sdiA 1936566..1937288 (+) 723 WP_024231281.1 transcriptional regulator SdiA -
  KFZ60_RS09260 (KFZ60_09235) yecF 1937356..1937580 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KFZ60_RS09265 (KFZ60_09240) yecU 1937567..1937743 (-) 177 WP_001307856.1 protein YecU -
  KFZ60_RS09270 (KFZ60_09245) letA 1938039..1938695 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KFZ60_RS09275 (KFZ60_09250) uvrC 1938692..1940524 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KFZ60_RS09280 (KFZ60_09255) pgsA 1940581..1941129 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KFZ60_RS09300 (KFZ60_09275) - 1941824..1942564 (-) 741 WP_088376142.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=598740 KFZ60_RS09270 WP_000611328.1 1938039..1938695(+) (letA) [Escherichia coli strain XJ34]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=598740 KFZ60_RS09270 WP_000611328.1 1938039..1938695(+) (letA) [Escherichia coli strain XJ34]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482