Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY13_RS13845 Genome accession   NZ_CP098219
Coordinates   2819151..2819807 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z0117EC0013     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2814151..2824807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY13_RS13805 (NBY13_13805) - 2814662..2814922 (+) 261 WP_000488108.1 ogr/Delta-like zinc finger family protein -
  NBY13_RS13810 (NBY13_13810) - 2815113..2815253 (+) 141 WP_000078920.1 Hok/Gef family protein -
  NBY13_RS13815 (NBY13_13815) - 2815443..2815724 (-) 282 WP_071529678.1 hypothetical protein -
  NBY13_RS13835 (NBY13_13835) pgsA 2816717..2817265 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NBY13_RS13840 (NBY13_13840) uvrC 2817322..2819154 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NBY13_RS13845 (NBY13_13845) letA 2819151..2819807 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NBY13_RS13850 (NBY13_13850) yecU 2820103..2820279 (+) 177 WP_001307856.1 protein YecU -
  NBY13_RS13855 (NBY13_13855) yecF 2820266..2820490 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NBY13_RS13860 (NBY13_13860) sdiA 2820558..2821280 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  NBY13_RS13865 (NBY13_13865) tcyN 2821510..2822262 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NBY13_RS13870 (NBY13_13870) tcyL 2822259..2822927 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NBY13_RS13875 (NBY13_13875) dcyD 2822942..2823928 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=598426 NBY13_RS13845 WP_000611328.1 2819151..2819807(-) (letA) [Escherichia coli strain Z0117EC0013]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=598426 NBY13_RS13845 WP_000611328.1 2819151..2819807(-) (letA) [Escherichia coli strain Z0117EC0013]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482