Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY15_RS10295 Genome accession   NZ_CP098214
Coordinates   2133361..2134017 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z0117EC0036     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2128361..2139017
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY15_RS10265 (NBY15_10260) dcyD 2129240..2130226 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  NBY15_RS10270 (NBY15_10265) tcyL 2130241..2130909 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NBY15_RS10275 (NBY15_10270) tcyN 2130906..2131658 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NBY15_RS10280 (NBY15_10275) sdiA 2131888..2132610 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  NBY15_RS10285 (NBY15_10280) yecF 2132678..2132902 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NBY15_RS10290 (NBY15_10285) yecU 2132889..2133065 (-) 177 WP_001307856.1 protein YecU -
  NBY15_RS10295 (NBY15_10290) letA 2133361..2134017 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NBY15_RS10300 (NBY15_10295) uvrC 2134014..2135846 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NBY15_RS10305 (NBY15_10300) pgsA 2135903..2136451 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NBY15_RS10325 (NBY15_10320) - 2137035..2138051 (-) 1017 WP_021560873.1 tyrosine-type recombinase/integrase -
  NBY15_RS10330 (NBY15_10325) - 2138020..2138283 (-) 264 WP_021560872.1 DUF4224 domain-containing protein -
  NBY15_RS10335 (NBY15_10330) - 2138219..2138443 (-) 225 WP_071780621.1 hypothetical protein -
  NBY15_RS10340 (NBY15_10335) - 2138493..2138675 (-) 183 WP_000916333.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=598254 NBY15_RS10295 WP_000611328.1 2133361..2134017(+) (letA) [Escherichia coli strain Z0117EC0036]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=598254 NBY15_RS10295 WP_000611328.1 2133361..2134017(+) (letA) [Escherichia coli strain Z0117EC0036]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482