Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY18_RS10670 Genome accession   NZ_CP098206
Coordinates   2223023..2223679 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain Z0117EC0054     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2218023..2228679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY18_RS10640 (NBY18_10640) dcyD 2218902..2219888 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  NBY18_RS10645 (NBY18_10645) tcyL 2219903..2220571 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NBY18_RS10650 (NBY18_10650) tcyN 2220568..2221320 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NBY18_RS10655 (NBY18_10655) sdiA 2221550..2222272 (+) 723 WP_167823480.1 transcriptional regulator SdiA -
  NBY18_RS10660 (NBY18_10660) yecF 2222340..2222564 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NBY18_RS10665 (NBY18_10665) yecU 2222551..2222727 (-) 177 WP_001307856.1 protein YecU -
  NBY18_RS10670 (NBY18_10670) letA 2223023..2223679 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NBY18_RS10675 (NBY18_10675) uvrC 2223676..2225508 (+) 1833 WP_001283434.1 excinuclease ABC subunit UvrC Machinery gene
  NBY18_RS10680 (NBY18_10680) pgsA 2225565..2226113 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NBY18_RS10700 (NBY18_10700) yecA 2226763..2227428 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=598005 NBY18_RS10670 WP_000611328.1 2223023..2223679(+) (letA) [Escherichia coli strain Z0117EC0054]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=598005 NBY18_RS10670 WP_000611328.1 2223023..2223679(+) (letA) [Escherichia coli strain Z0117EC0054]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482