Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NBY23_RS14555 Genome accession   NZ_CP098195
Coordinates   2925814..2926470 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Z0117EC0098     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2920814..2931470
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NBY23_RS14525 (NBY23_14525) yecA 2922065..2922730 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  NBY23_RS14545 (NBY23_14545) pgsA 2923380..2923928 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NBY23_RS14550 (NBY23_14550) uvrC 2923985..2925817 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NBY23_RS14555 (NBY23_14555) letA 2925814..2926470 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NBY23_RS25290 - 2926612..2926728 (+) 117 WP_001302039.1 hypothetical protein -
  NBY23_RS14560 (NBY23_14560) yecU 2926766..2926942 (+) 177 WP_000590344.1 protein YecU -
  NBY23_RS14565 (NBY23_14565) yecF 2926929..2927153 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NBY23_RS14570 (NBY23_14570) sdiA 2927221..2927943 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  NBY23_RS14575 (NBY23_14575) tcyN 2928173..2928925 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NBY23_RS14580 (NBY23_14580) tcyL 2928922..2929590 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  NBY23_RS14585 (NBY23_14585) dcyD 2929605..2930591 (-) 987 WP_001724631.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=597673 NBY23_RS14555 WP_000611335.1 2925814..2926470(-) (letA) [Escherichia coli strain Z0117EC0098]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=597673 NBY23_RS14555 WP_000611335.1 2925814..2926470(-) (letA) [Escherichia coli strain Z0117EC0098]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486