Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NAG70_RS08945 Genome accession   NZ_CP097882
Coordinates   1873415..1874071 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1868415..1879071
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NAG70_RS08915 dcyD 1869294..1870280 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NAG70_RS08920 tcyL 1870295..1870963 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NAG70_RS08925 tcyN 1870960..1871712 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NAG70_RS08930 sdiA 1871942..1872664 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  NAG70_RS08935 yecF 1872732..1872956 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NAG70_RS08940 yecU 1872943..1873119 (-) 177 WP_000590347.1 protein YecU -
  NAG70_RS22830 - 1873202..1873273 (-) 72 Protein_1747 transcriptional regulator -
  NAG70_RS08945 letA 1873415..1874071 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NAG70_RS08950 uvrC 1874068..1875900 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NAG70_RS08955 pgsA 1875957..1876505 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NAG70_RS08975 yecA 1877155..1877820 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=596950 NAG70_RS08945 WP_000611335.1 1873415..1874071(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=596950 NAG70_RS08945 WP_000611335.1 1873415..1874071(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486