Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NAG69_RS09035 Genome accession   NZ_CP097881
Coordinates   1888368..1889024 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli str. K-12 substr. MG1655 strain K-12     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1883368..1894024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NAG69_RS09005 dcyD 1884247..1885233 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  NAG69_RS09010 tcyL 1885248..1885916 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  NAG69_RS09015 tcyN 1885913..1886665 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NAG69_RS09020 sdiA 1886895..1887617 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  NAG69_RS09025 yecF 1887685..1887909 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  NAG69_RS09030 yecU 1887896..1888072 (-) 177 WP_000590347.1 protein YecU -
  NAG69_RS22395 - 1888155..1888226 (-) 72 Protein_1765 transcriptional regulator -
  NAG69_RS09035 letA 1888368..1889024 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NAG69_RS09040 uvrC 1889021..1890853 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  NAG69_RS09045 pgsA 1890910..1891458 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NAG69_RS09065 yecA 1892108..1892773 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=596870 NAG69_RS09035 WP_000611335.1 1888368..1889024(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=596870 NAG69_RS09035 WP_000611335.1 1888368..1889024(+) (letA) [Escherichia coli str. K-12 substr. MG1655 strain K-12]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486