Detailed information NTG0596513

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: K4756_RS12635
• Genome accession: NZ_CP081458
• Coordinates: 2457131..2459461 (-)
• Length: 776 a.a.
• NCBI ID: WP_041517945.1
• Uniprot ID: -
• Organism: Bacillus subtilis subsp. subtilis strain ps4060
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2452131..2464461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K4756_RS12600 (K4756_12530)	yqxA	2452470..2452808 (-)	339	WP_014477382.1	YqxA family protein	-
K4756_RS12605 (K4756_12535)	spoIIP	2452825..2454030 (-)	1206	WP_015384129.1	spore autolysin SpoIIP	-
K4756_RS12610 (K4756_12540)	gpr	2454093..2455199 (-)	1107	WP_014480309.1	GPR endopeptidase	-
K4756_RS12615 (K4756_12545)	rpsT	2455403..2455669 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
K4756_RS12620 (K4756_12550)	holA	2455684..2456727 (-)	1044	WP_015384130.1	DNA polymerase III subunit delta	-
K4756_RS12625 (K4756_12555)	-	2456767..2456916 (-)	150	WP_003229985.1	hypothetical protein	-
K4756_RS12630 (K4756_12560)	yqzM	2456957..2457091 (+)	135	WP_003229983.1	YqzM family protein	-
K4756_RS12635 (K4756_12565)	comEC	2457131..2459461 (-)	2331	WP_041517945.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
K4756_RS12640 (K4756_12570)	comEB	2459465..2460034 (-)	570	WP_003229978.1	ComE operon protein 2	-
K4756_RS12645 (K4756_12575)	comEA	2460101..2460718 (-)	618	WP_015384132.1	competence protein ComEA	Machinery gene
K4756_RS12650 (K4756_12580)	comER	2460802..2461623 (+)	822	WP_004398597.1	late competence protein ComER	-
K4756_RS12655 (K4756_12585)	yqeM	2461689..2462432 (-)	744	WP_015384134.1	class I SAM-dependent DNA methyltransferase	-
K4756_RS12660 (K4756_12590)	rsfS	2462429..2462785 (-)	357	WP_014480315.1	ribosome silencing factor	-
K4756_RS12665 (K4756_12595)	yqeK	2462803..2463363 (-)	561	WP_015483448.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
K4756_RS12670 (K4756_12600)	nadD	2463353..2463922 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
K4756_RS12675 (K4756_12605)	yhbY	2463934..2464224 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86647.97 Da
• Isoelectric Point: 6.8607

>NTDB_id=596513 K4756_RS12635 WP_041517945.1 2457131..2459461(-) (comEC) [Bacillus subtilis subsp. subtilis strain ps4060]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDNIPKIDGDRMSMMVETPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAASSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHKFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVTILLLLMAIEKRSLSQLMVTGG
ICCTVLFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKYHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFTQQLQPETAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRGGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=596513 K4756_RS12635 WP_041517945.1 2457131..2459461(-) (comEC) [Bacillus subtilis subsp. subtilis strain ps4060]
ATGCGTAATTCGCGATTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACTTATCAATTC
AAGGCAGTGATTGACAATATTCCTAAAATTGACGGCGACCGTATGTCTATGATGGTTGAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATCCAAAACTGCAGCGAACCTGAAAATTTCAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTCTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAAGATGAAGTGCTTACTGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGGCTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATACGCCTTGGTATAACAAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTTCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATAAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCTGATGTTGATGTATTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCCTCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACTGGAGGC
ATTTGCTGCACGGTGCTGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGTATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
GCACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCACCCAACAGCTTCAGCCGGAAACGGCCATTATCTCAGCTGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGGTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978