Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M9O79_RS09245 Genome accession   NZ_CP097721
Coordinates   1921662..1922318 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MS1665     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1916662..1927318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9O79_RS09215 (M9O79_09220) dcyD 1917542..1918528 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M9O79_RS09220 (M9O79_09225) tcyL 1918543..1919211 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M9O79_RS09225 (M9O79_09230) tcyN 1919208..1919960 (+) 753 WP_001273009.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M9O79_RS09230 (M9O79_09235) sdiA 1920190..1920912 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  M9O79_RS09235 (M9O79_09240) yecF 1920979..1921203 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M9O79_RS09240 (M9O79_09245) yecU 1921190..1921366 (-) 177 WP_000590347.1 protein YecU -
  M9O79_RS23735 - 1921449..1921520 (-) 72 Protein_1807 transcriptional regulator -
  M9O79_RS09245 (M9O79_09250) letA 1921662..1922318 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M9O79_RS09250 (M9O79_09255) uvrC 1922315..1924147 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M9O79_RS09255 (M9O79_09260) pgsA 1924204..1924752 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M9O79_RS09275 (M9O79_09280) yecA 1925402..1926067 (+) 666 WP_154813122.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=596268 M9O79_RS09245 WP_000611335.1 1921662..1922318(+) (letA) [Escherichia coli strain MS1665]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=596268 M9O79_RS09245 WP_000611335.1 1921662..1922318(+) (letA) [Escherichia coli strain MS1665]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486