Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M9O77_RS10060 Genome accession   NZ_CP097716
Coordinates   2104555..2105211 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MS1718     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2099555..2110211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9O77_RS10030 (M9O77_10040) dcyD 2100435..2101421 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  M9O77_RS10035 (M9O77_10045) tcyL 2101436..2102104 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M9O77_RS10040 (M9O77_10050) tcyN 2102101..2102853 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M9O77_RS10045 (M9O77_10055) sdiA 2103083..2103805 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  M9O77_RS10050 (M9O77_10060) yecF 2103872..2104096 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M9O77_RS10055 (M9O77_10065) yecU 2104083..2104259 (-) 177 WP_001307856.1 protein YecU -
  M9O77_RS10060 (M9O77_10070) letA 2104555..2105211 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M9O77_RS10065 (M9O77_10075) uvrC 2105208..2107040 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M9O77_RS10070 (M9O77_10080) pgsA 2107097..2107645 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M9O77_RS10090 (M9O77_10100) - 2108343..2108984 (-) 642 Protein_1970 hypothetical protein -
  M9O77_RS10095 (M9O77_10105) - 2109057..2110145 (+) 1089 Protein_1971 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=596102 M9O77_RS10060 WP_000611328.1 2104555..2105211(+) (letA) [Escherichia coli strain MS1718]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=596102 M9O77_RS10060 WP_000611328.1 2104555..2105211(+) (letA) [Escherichia coli strain MS1718]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482