Detailed information NTG0594887

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HLV54_RS13590
• Genome accession: NZ_CP080770
• Coordinates: 2730913..2731800 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143422.1
• Uniprot ID: A0AB73JC73
• Organism: Staphylococcus aureus strain HL23187
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2725913..2736800

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLV54_RS13560 (HLV54_002712)	-	2725922..2726014 (+)	93	WP_010956583.1	hypothetical protein	-
HLV54_RS13565 (HLV54_002713)	-	2726122..2726619 (-)	498	WP_001065268.1	glutathione peroxidase	-
HLV54_RS13570 (HLV54_002714)	-	2726629..2726889 (-)	261	WP_011382405.1	hypothetical protein	-
HLV54_RS13575 (HLV54_002715)	-	2727271..2727384 (-)	114	WP_078065157.1	hypothetical protein	-
HLV54_RS13580 (HLV54_002716)	-	2728053..2730053 (-)	2001	WP_170171893.1	ABC transporter permease	-
HLV54_RS13585 (HLV54_002717)	-	2730050..2730805 (-)	756	WP_000923775.1	ABC transporter ATP-binding protein	-
HLV54_RS13590 (HLV54_002718)	braS	2730913..2731800 (-)	888	WP_000143422.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HLV54_RS13595 (HLV54_002719)	braR	2731811..2732476 (-)	666	WP_000697884.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HLV54_RS13600 (HLV54_002720)	-	2732502..2732702 (-)	201	WP_000604725.1	hypothetical protein	-
HLV54_RS13605 (HLV54_002721)	-	2732900..2734324 (+)	1425	WP_000953738.1	alkaline phosphatase	-
HLV54_RS14330	-	2734384..2734485 (-)	102	WP_000731972.1	SE2200 family small protein	-
HLV54_RS13615 (HLV54_002723)	-	2734607..2735062 (-)	456	WP_000106183.1	MarR family winged helix-turn-helix transcriptional regulator	-
HLV54_RS13620 (HLV54_002724)	-	2735307..2736068 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34031.29 Da
• Isoelectric Point: 5.8962

>NTDB_id=594887 HLV54_RS13590 WP_000143422.1 2730913..2731800(-) (braS) [Staphylococcus aureus strain HL23187]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGVGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=594887 HLV54_RS13590 WP_000143422.1 2730913..2731800(-) (braS) [Staphylococcus aureus strain HL23187]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTGTTGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99