Detailed information NTG0594039

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: JMO07_RS09235
• Genome accession: NZ_CP080564
• Coordinates: 1911172..1912215 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain HL16278
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1906172..1917215

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JMO07_RS09205 (JMO07_001845)	-	1906594..1907850 (-)	1257	WP_001789555.1	aminopeptidase	-
JMO07_RS09210 (JMO07_001846)	-	1907853..1908053 (-)	201	WP_000180460.1	DUF1128 family protein	-
JMO07_RS09215 (JMO07_001847)	-	1908200..1908664 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
JMO07_RS09220 (JMO07_001848)	-	1908671..1908946 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
JMO07_RS09225 (JMO07_001849)	-	1909224..1910441 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
JMO07_RS09230 (JMO07_001850)	vraR	1910553..1911182 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
JMO07_RS09235 (JMO07_001851)	vraS	1911172..1912215 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
JMO07_RS09240 (JMO07_001852)	liaF	1912212..1912913 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
JMO07_RS09245 (JMO07_001853)	-	1912928..1913314 (-)	387	WP_001110179.1	hypothetical protein	-
JMO07_RS09250 (JMO07_001854)	map	1913531..1914289 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
JMO07_RS09255 (JMO07_001855)	-	1914817..1915803 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
JMO07_RS09260 (JMO07_001856)	-	1916234..1916647 (-)	414	WP_025173836.1	hypothetical protein	-
JMO07_RS09265 (JMO07_001857)	-	1916676..1916786 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=594039 JMO07_RS09235 WP_001017131.1 1911172..1912215(-) (vraS) [Staphylococcus aureus strain HL16278]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=594039 JMO07_RS09235 WP_001017131.1 1911172..1912215(-) (vraS) [Staphylococcus aureus strain HL16278]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1