Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M4R35_RS09670 Genome accession   NZ_CP097181
Coordinates   1972081..1972737 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SH21PTE31     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1967081..1977737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M4R35_RS09640 dcyD 1967960..1968946 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M4R35_RS09645 tcyL 1968961..1969629 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M4R35_RS09650 tcyN 1969626..1970378 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M4R35_RS09655 sdiA 1970608..1971330 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  M4R35_RS09660 yecF 1971398..1971622 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M4R35_RS09665 yecU 1971609..1971785 (-) 177 WP_000590344.1 protein YecU -
  M4R35_RS24065 - 1971823..1971939 (-) 117 WP_071889271.1 transcriptional regulator -
  M4R35_RS09670 letA 1972081..1972737 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M4R35_RS09675 uvrC 1972734..1974566 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M4R35_RS09680 pgsA 1974623..1975171 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M4R35_RS09700 - 1975867..1976607 (-) 741 WP_034167755.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=593859 M4R35_RS09670 WP_000611335.1 1972081..1972737(+) (letA) [Escherichia coli strain SH21PTE31]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=593859 M4R35_RS09670 WP_000611335.1 1972081..1972737(+) (letA) [Escherichia coli strain SH21PTE31]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACTTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486