Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   LDH51_RS11380 Genome accession   NZ_CP097001
Coordinates   2292844..2293500 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain NCCP 15734     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2287844..2298500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDH51_RS11345 dcyD 2288724..2289710 (+) 987 WP_042033531.1 D-cysteine desulfhydrase -
  LDH51_RS11350 tcyL 2289725..2290393 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  LDH51_RS11355 tcyN 2290390..2291142 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  LDH51_RS11360 sdiA 2291372..2292094 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  LDH51_RS11365 yecF 2292161..2292385 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  LDH51_RS11370 yecU 2292372..2292548 (-) 177 WP_000590344.1 protein YecU -
  LDH51_RS11375 - 2292586..2292702 (-) 117 WP_001302039.1 hypothetical protein -
  LDH51_RS11380 letA 2292844..2293500 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  LDH51_RS11385 uvrC 2293497..2295329 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  LDH51_RS11390 pgsA 2295386..2295934 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  LDH51_RS11410 - 2296929..2297210 (+) 282 WP_071529678.1 hypothetical protein -
  LDH51_RS11415 - 2297400..2297540 (-) 141 WP_000078920.1 Hok/Gef family protein -
  LDH51_RS11420 - 2297730..2297990 (-) 261 WP_000488108.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=593288 LDH51_RS11380 WP_000611328.1 2292844..2293500(+) (letA) [Escherichia coli strain NCCP 15734]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=593288 LDH51_RS11380 WP_000611328.1 2292844..2293500(+) (letA) [Escherichia coli strain NCCP 15734]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482