Detailed information NTG0059327

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CA347_RS10170
• Genome accession: NC_021554
• Coordinates: 2023562..2024605 (-)
• Length: 347 a.a.
• NCBI ID: WP_016528753.1
• Uniprot ID: -
• Organism: Staphylococcus aureus CA-347
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2018562..2029605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CA347_RS10140 (CA347_1966)	-	2018983..2020230 (-)	1248	WP_001622131.1	aminopeptidase	-
CA347_RS10145 (CA347_1967)	-	2020242..2020442 (-)	201	WP_000180459.1	DUF1128 family protein	-
CA347_RS10150 (CA347_1968)	-	2020589..2021053 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
CA347_RS10155 (CA347_1969)	-	2021060..2021335 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CA347_RS10160 (CA347_1970)	-	2021613..2022830 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
CA347_RS10165 (CA347_1971)	vraR	2022943..2023572 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CA347_RS10170 (CA347_1972)	vraS	2023562..2024605 (-)	1044	WP_016528753.1	sensor histidine kinase	Regulator
CA347_RS10175 (CA347_1973)	liaF	2024602..2025303 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CA347_RS10180 (CA347_1974)	-	2025318..2025704 (-)	387	WP_001110184.1	hypothetical protein	-
CA347_RS10185 (CA347_1975)	map	2025921..2026679 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
CA347_RS10195 (CA347_1976)	-	2027322..2028308 (+)	987	WP_000999713.1	FUSC family protein	-
CA347_RS10200 (CA347_1977)	-	2028486..2028899 (-)	414	WP_001622129.1	hypothetical protein	-
CA347_RS10205	-	2028928..2029037 (-)	110	Protein_1953	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40086.60 Da
• Isoelectric Point: 6.0577

>NTDB_id=59327 CA347_RS10170 WP_016528753.1 2023562..2024605(-) (vraS) [Staphylococcus aureus CA-347]
MNHYIRTIVSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=59327 CA347_RS10170 WP_016528753.1 2023562..2024605(-) (vraS) [Staphylococcus aureus CA-347]
ATGAACCACTACATTAGAACAATTGTTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997