Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M2894_RS10185 Genome accession   NZ_CP096976
Coordinates   2129405..2130061 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 17-07187     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2124405..2135061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2894_RS10155 (M2894_10155) dcyD 2125284..2126270 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M2894_RS10160 (M2894_10160) tcyL 2126285..2126953 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M2894_RS10165 (M2894_10165) tcyN 2126950..2127702 (+) 753 WP_001272980.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M2894_RS10170 (M2894_10170) sdiA 2127932..2128654 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  M2894_RS10175 (M2894_10175) yecF 2128722..2128946 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M2894_RS10180 (M2894_10180) yecU 2128933..2129109 (-) 177 WP_000590344.1 protein YecU -
  M2894_RS26575 - 2129147..2129263 (-) 117 Protein_1995 transcriptional regulator -
  M2894_RS10185 (M2894_10185) letA 2129405..2130061 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M2894_RS10190 (M2894_10190) uvrC 2130058..2131890 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M2894_RS10195 (M2894_10195) pgsA 2131947..2132495 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M2894_RS10215 (M2894_10215) yecA 2133145..2133810 (+) 666 WP_000847876.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=593210 M2894_RS10185 WP_000611335.1 2129405..2130061(+) (letA) [Escherichia coli strain 17-07187]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=593210 M2894_RS10185 WP_000611335.1 2129405..2130061(+) (letA) [Escherichia coli strain 17-07187]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486