Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   K1T74_RS12130 Genome accession   NZ_CP080462
Coordinates   2660926..2661537 (+) Length   203 a.a.
NCBI ID   WP_000340100.1    Uniprot ID   Q4F6W7
Organism   Vibrio cholerae strain ICDC-VC702     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2655926..2666537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K1T74_RS12110 - 2656318..2657235 (-) 918 WP_220106266.1 ABC transporter ATP-binding protein -
  K1T74_RS12115 - 2657554..2659206 (-) 1653 WP_220105825.1 SulP family inorganic anion transporter -
  K1T74_RS12120 can 2659354..2660022 (+) 669 WP_001114117.1 carbonate dehydratase -
  K1T74_RS12125 hpt 2660097..2660630 (-) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  K1T74_RS12130 hapR 2660926..2661537 (+) 612 WP_000340100.1 quorum-sensing master transcriptional regulator HapR Regulator
  K1T74_RS12135 rsmI 2661750..2662616 (-) 867 WP_000131549.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  K1T74_RS12140 - 2662686..2664491 (+) 1806 WP_001015477.1 penicillin-binding protein activator -
  K1T74_RS12145 - 2664478..2664846 (+) 369 WP_001893625.1 YraN family protein -
  K1T74_RS12150 - 2664850..2665440 (+) 591 WP_000887295.1 phosphoheptose isomerase -
  K1T74_RS12155 - 2665443..2666012 (+) 570 WP_000836325.1 BON domain-containing protein -
  K1T74_RS12160 tnpA 2666096..2666533 (-) 438 WP_000503164.1 IS200/IS605-like element IS1004 family transposase -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23720.44 Da        Isoelectric Point: 6.6356

>NTDB_id=593061 K1T74_RS12130 WP_000340100.1 2660926..2661537(+) (hapR) [Vibrio cholerae strain ICDC-VC702]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLVDSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=593061 K1T74_RS12130 WP_000340100.1 2660926..2661537(+) (hapR) [Vibrio cholerae strain ICDC-VC702]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGAAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTTTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCTATGGAACGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGTATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGCTGGTCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4F6W7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

99.507

100

0.995
  hapR Vibrio cholerae strain A1552

99.507

100

0.995
  opaR Vibrio parahaemolyticus RIMD 2210633

72.727

97.537

0.709