Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   KZW86_RS00270 Genome accession   NZ_CP080249
Coordinates   58068..59696 (-) Length   542 a.a.
NCBI ID   WP_011302038.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NV_1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 24197..97220 58068..59696 within 0
SCCmec 39615..61066 58068..59696 within 0


Gene organization within MGE regions


Location: 24197..97220
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZW86_RS00100 (KZW86_00100) yycF 24784..25485 (+) 702 WP_000101976.1 response regulator YycF -
  KZW86_RS00105 (KZW86_00105) walK 25498..27324 (+) 1827 WP_000871607.1 cell wall metabolism sensor histidine kinase WalK -
  KZW86_RS00110 (KZW86_00110) yycH 27317..28651 (+) 1335 WP_153906603.1 two-component system activity regulator YycH -
  KZW86_RS00115 (KZW86_00115) yycI 28652..29440 (+) 789 WP_001104165.1 two-component system regulatory protein YycI -
  KZW86_RS00120 (KZW86_00120) - 29829..30629 (+) 801 WP_000088649.1 MBL fold metallo-hydrolase -
  KZW86_RS00125 (KZW86_00125) adsA 30856..33174 (+) 2319 WP_000645787.1 LPXTG-anchored adenosine synthase AdsA -
  KZW86_RS00130 (KZW86_00130) rlmH 33542..34021 (+) 480 WP_000704775.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  KZW86_RS00135 (KZW86_00135) - 34343..35599 (+) 1257 WP_153906604.1 DUF3578 domain-containing protein -
  KZW86_RS00140 (KZW86_00140) - 36014..36253 (+) 240 WP_001282728.1 hypothetical protein -
  KZW86_RS00145 (KZW86_00145) - 36285..36959 (-) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  KZW86_RS00150 (KZW86_00150) - 37043..37384 (+) 342 WP_001797647.1 hydroxymethylglutaryl-CoA synthase -
  KZW86_RS00155 (KZW86_00155) - 38301..39044 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  KZW86_RS00160 (KZW86_00160) - 39141..39569 (+) 429 WP_000872606.1 MaoC family dehydratase -
  KZW86_RS00165 (KZW86_00165) mecA 39615..41624 (-) 2010 WP_063852655.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  KZW86_RS00170 (KZW86_00170) mecR1 41721..43478 (+) 1758 WP_234769142.1 beta-lactam sensor/signal transducer MecR1 -
  KZW86_RS00175 (KZW86_00175) mecI 43478..43849 (+) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  KZW86_RS00180 (KZW86_00180) psm-mec 43934..44002 (-) 69 WP_014532405.1 phenol-soluble modulin PSM-mec -
  KZW86_RS00185 (KZW86_00185) - 44322..45470 (+) 1149 WP_000427807.1 ROK family transcriptional regulator -
  KZW86_RS00190 (KZW86_00190) cstB 45584..46918 (-) 1335 Protein_35 persulfide dioxygenase-sulfurtransferase CstB -
  KZW86_RS00195 (KZW86_00195) - 46951..48015 (-) 1065 WP_000438836.1 DsrE/DsrF/DrsH-like family protein -
  KZW86_RS00200 (KZW86_00200) cstR 48151..48411 (+) 261 WP_000220507.1 persulfide-sensing transcriptional repressor CstR -
  KZW86_RS00205 (KZW86_00205) - 48411..49049 (+) 639 Protein_38 sulfite exporter TauE/SafE family protein -
  KZW86_RS00215 (KZW86_00215) - 49604..49765 (+) 162 WP_159083127.1 hypothetical protein -
  KZW86_RS00220 (KZW86_00220) fexA 50001..51428 (+) 1428 WP_115118130.1 chloramphenicol/florfenicol efflux MFS transporter FexA -
  KZW86_RS00225 (KZW86_00225) - 51606..52148 (+) 543 WP_031590464.1 NAD(P)H-dependent oxidoreductase -
  KZW86_RS00230 (KZW86_00230) - 52305..52670 (-) 366 WP_000619629.1 DUF6262 family protein -
  KZW86_RS00235 (KZW86_00235) - 52672..54585 (-) 1914 WP_031590465.1 site-specific integrase -
  KZW86_RS00240 - 54588..55671 (-) 1084 Protein_44 tyrosine-type recombinase/integrase -
  KZW86_RS00245 (KZW86_00250) - 55785..56111 (-) 327 WP_234769200.1 JAB domain-containing protein -
  KZW86_RS00250 (KZW86_00255) - 56104..56310 (-) 207 WP_114604133.1 hypothetical protein -
  KZW86_RS00255 (KZW86_00260) - 56312..56830 (-) 519 WP_153906605.1 DUF1643 domain-containing protein -
  KZW86_RS00260 (KZW86_00265) - 56848..57159 (-) 312 WP_153906606.1 DUF960 family protein -
  KZW86_RS00265 (KZW86_00270) - 57255..57593 (-) 339 WP_011302037.1 SAUGI family uracil-DNA glycosylase inhibitor -
  KZW86_RS00270 (KZW86_00275) ccrB 58068..59696 (-) 1629 WP_011302038.1 recombinase family protein Machinery gene
  KZW86_RS00275 (KZW86_00280) ccrA 59717..61066 (-) 1350 WP_011302039.1 recombinase family protein Machinery gene
  KZW86_RS00280 (KZW86_00285) - 61244..61501 (-) 258 WP_011302040.1 hypothetical protein -
  KZW86_RS00285 (KZW86_00290) - 61566..63314 (-) 1749 WP_228766655.1 DUF927 domain-containing protein -
  KZW86_RS00290 (KZW86_00295) - 63362..63652 (-) 291 WP_113587732.1 DUF1413 domain-containing protein -
  KZW86_RS00295 (KZW86_00300) - 63834..64835 (-) 1002 WP_151130518.1 hypothetical protein -
  KZW86_RS00300 (KZW86_00305) - 65019..65585 (+) 567 WP_031869230.1 hypothetical protein -
  KZW86_RS00305 (KZW86_00310) - 65588..66337 (+) 750 WP_031869231.1 adenylate/guanylate cyclase domain-containing protein -
  KZW86_RS00310 (KZW86_00315) - 66710..66844 (-) 135 WP_001790628.1 hypothetical protein -
  KZW86_RS00315 (KZW86_00320) - 66808..66900 (+) 93 WP_001790000.1 hypothetical protein -
  KZW86_RS00320 (KZW86_00325) - 67047..68792 (+) 1746 WP_000700190.1 DUF6119 family protein -
  KZW86_RS00325 (KZW86_00330) - 68890..69246 (-) 357 Protein_61 tRNA-dihydrouridine synthase -
  KZW86_RS00330 (KZW86_00335) - 69551..69639 (-) 89 Protein_62 hypothetical protein -
  KZW86_RS00335 (KZW86_00340) - 69737..70492 (-) 756 WP_000355845.1 sulfite exporter TauE/SafE family protein -
  KZW86_RS00340 (KZW86_00345) cstR 70492..70752 (-) 261 WP_001105088.1 persulfide-sensing transcriptional repressor CstR -
  KZW86_RS00345 (KZW86_00350) cstA 70889..71953 (+) 1065 WP_000816133.1 persulfide response sulfurtransferase CstA -
  KZW86_RS00350 (KZW86_00355) cstB 71984..73318 (+) 1335 WP_000465472.1 persulfide dioxygenase-sulfurtransferase CstB -
  KZW86_RS00355 (KZW86_00360) sqr 73337..74530 (+) 1194 WP_001033018.1 type II sulfide:quinone oxidoreductase Sqr -
  KZW86_RS15000 - 74797..75011 (-) 215 Protein_68 universal stress protein -
  KZW86_RS00360 (KZW86_00365) - 75197..76183 (-) 987 WP_000662022.1 tRNA-dihydrouridine synthase -
  KZW86_RS00365 (KZW86_00370) - 76492..76695 (+) 204 WP_000389759.1 DUF6007 family protein -
  KZW86_RS00370 (KZW86_00375) - 76744..77040 (+) 297 WP_000201644.1 TfoX/Sxy family protein -
  KZW86_RS00375 (KZW86_00380) - 77248..77850 (+) 603 WP_000908956.1 hypothetical protein -
  KZW86_RS00380 (KZW86_00385) - 78117..81269 (+) 3153 WP_000080564.1 DEAD/DEAH box helicase -
  KZW86_RS00385 (KZW86_00390) - 81326..81808 (+) 483 WP_000410567.1 hypothetical protein -
  KZW86_RS00390 (KZW86_00395) - 82014..83000 (+) 987 WP_000710555.1 phosphatidylinositol-specific phospholipase C -
  KZW86_RS00395 (KZW86_00400) - 83221..83991 (+) 771 WP_000977777.1 tandem-type lipoprotein -
  KZW86_RS00400 (KZW86_00405) - 84043..84813 (+) 771 WP_000597207.1 tandem-type lipoprotein -
  KZW86_RS00405 (KZW86_00410) - 84878..85183 (+) 306 Protein_78 Csa1 family protein -
  KZW86_RS00410 (KZW86_00415) - 85434..85925 (-) 492 WP_001667277.1 IS30 family transposase -
  KZW86_RS00415 (KZW86_00420) - 85891..86397 (-) 507 WP_000163139.1 helix-turn-helix domain-containing protein -
  KZW86_RS00420 (KZW86_00425) - 86509..86871 (-) 363 WP_000166624.1 cystatin-like fold lipoprotein -
  KZW86_RS00425 (KZW86_00430) - 86920..87513 (-) 594 WP_000768323.1 hypothetical protein -
  KZW86_RS00430 (KZW86_00435) - 87520..88557 (-) 1038 WP_000247512.1 CHAP domain-containing protein -
  KZW86_RS00435 (KZW86_00440) - 88547..90460 (-) 1914 WP_000824165.1 ABC transporter permease -
  KZW86_RS00440 (KZW86_00445) - 90476..90643 (-) 168 WP_001031438.1 hypothetical protein -
  KZW86_RS00445 (KZW86_00450) - 90656..92011 (-) 1356 WP_000178428.1 FtsK/SpoIIIE domain-containing protein -
  KZW86_RS00450 (KZW86_00455) - 92069..92317 (-) 249 WP_001258263.1 hypothetical protein -
  KZW86_RS00455 (KZW86_00460) - 93422..95916 (-) 2495 Protein_88 ATP-binding protein -
  KZW86_RS00460 (KZW86_00465) - 95951..96340 (-) 390 WP_000358149.1 TcpE family conjugal transfer membrane protein -
  KZW86_RS00465 (KZW86_00470) - 96346..96606 (-) 261 WP_000400523.1 TcpD family membrane protein -

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62354.36 Da        Isoelectric Point: 9.6600

>NTDB_id=591650 KZW86_RS00270 WP_011302038.1 58068..59696(-) (ccrB) [Staphylococcus aureus strain NV_1]
MQQLKQKRVGIYVRVSTEMQSAEGYSIDGQINQIKEYCNFHHFEVKDIYADRGISGKSMNRPALQRMLHDANKGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNTILENIYTGQHQRALEGYYQGN
LPLGYNNIPDNKKDLMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAK
YKDWNDKRRKGLNDKPVIAEGKHAPIIGKDLWDKVQARKKQVSEKPQVHGKGTNILTGLISCPQCSASMSASTTVNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVIKQVVERVNQEHQIDMAALNHDIAYKQQQYD
EVQIKLDNLIKTLEDNPDLTSVLKNTIHQYEKQLNDITTQINQLKQQQNQEKPSYDTKQIAALLQQIFQNVESMDKVQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNDTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=591650 KZW86_RS00270 WP_011302038.1 58068..59696(-) (ccrB) [Staphylococcus aureus strain NV_1]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTCCGCGTATCAACAGAAATGCAAAGTGCAGAGGGTTATAGTAT
CGACGGTCAAATCAATCAAATCAAAGAATATTGTAACTTCCATCATTTCGAAGTCAAAGATATATACGCTGATCGTGGTA
TTTCAGGAAAGTCTATGAACCGCCCTGCACTTCAACGTATGTTACATGATGCGAATAAAGGTCATATTGATTGTGTTATG
GTGTATAAAACAAATCGACTCGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATGTCGA
ATTTTTCAGTTTGTCTGAGCGTATGGAAGTCAACACTTCTTCTGGTAAACTCATGTTACAAATACTTGCAAGTTTTTCCG
AATTTGAAAGAAATACCATTTTAGAGAATATTTACACCGGACAACATCAAAGAGCCTTAGAAGGCTATTACCAAGGTAAT
CTTCCTTTAGGATATAATAACATACCAGATAATAAAAAAGATTTGATGATTAATCAGCATGAAGCTAATATTGTGAAATA
TATTTTTGAATCTTACGCCAAAGGTCATGGTTATCGTAAAATTGCCAACGCACTCAATCATAAAGGTTATGTCACTAAGA
AAGGTAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCTAAA
TACAAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAGCCAGTAATCGCTGAAGGTAAGCACGCCCCTATTAT
TGGCAAAGACTTATGGGATAAAGTCCAAGCACGTAAAAAACAAGTAAGTGAAAAACCACAAGTTCATGGTAAAGGAACCA
ATATTTTAACTGGATTAATTTCGTGTCCCCAATGTTCTGCTTCAATGTCTGCGAGCACAACAGTTAATACACTTAAAGAT
GGTACTAAAAAACGCATTCGCTACTATTCGTGTAGTAACTTTCGTAATAAAGGGTCAAAAGTATGTTCTGCGAATAGTGT
CAGAGCCGATGTAATTGAAAAATATGTTATGGATCAAATACTCGAAATTGTTAAAAGCGACAAGGTTATCAAGCAAGTCG
TTGAGCGTGTCAATCAAGAACATCAAATTGATATGGCTGCACTCAATCATGATATCGCATATAAGCAACAACAATATGAT
GAGGTCCAAATCAAATTAGATAACTTGATAAAAACGCTTGAAGATAATCCAGACTTAACATCTGTGCTTAAAAATACGAT
TCATCAGTATGAAAAACAACTCAATGACATCACAACTCAAATCAATCAACTTAAGCAACAACAAAATCAAGAGAAACCAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACAAATATTTCAAAACGTAGAATCAATGGATAAAGTACAACTCAAA
GCATTATACCTTACGGTCATTGATCGTATCGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTCAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATGATACCCCACTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACACTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(11-155)

Recombinase (Recombinase)

(180-280)

Ogr/Delta-like zinc finger (Ogr_Delta)

(302-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

83.764

100

0.838