Detailed information NTG0590314

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: KZA74_RS19675
• Genome accession: NZ_CP079931
• Coordinates: 3533527..3534387 (+)
• Length: 286 a.a.
• NCBI ID: WP_001152268.1
• Uniprot ID: A0A1E3M8A8
• Organism: Acinetobacter baumannii strain 17978UN
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3528527..3539387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZA74_RS16755 (KZA74_16765)	secG	3529132..3529461 (-)	330	WP_000555570.1	preprotein translocase subunit SecG	-
KZA74_RS16760 (KZA74_16770)	tpiA	3529474..3530268 (-)	795	WP_000016939.1	triose-phosphate isomerase	-
KZA74_RS16765 (KZA74_16775)	pilB	3530559..3532271 (+)	1713	WP_001274983.1	type IV-A pilus assembly ATPase PilB	Machinery gene
KZA74_RS16770 (KZA74_16780)	pilC	3532301..3533527 (+)	1227	WP_000279216.1	type II secretion system F family protein	Machinery gene
KZA74_RS19675 (KZA74_16785)	pilD	3533527..3534387 (+)	861	WP_001152268.1	prepilin peptidase	Machinery gene
KZA74_RS16780 (KZA74_16790)	coaE	3534389..3534985 (+)	597	WP_000874127.1	dephospho-CoA kinase	-
KZA74_RS16785 (KZA74_16795)	-	3534982..3535899 (-)	918	WP_000075016.1	DMT family transporter	-
KZA74_RS16790 (KZA74_16800)	rlmB	3535935..3536684 (-)	750	WP_001118149.1	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	-
KZA74_RS16795 (KZA74_16805)	-	3536786..3537112 (-)	327	WP_000099685.1	pyrimidine/purine nucleoside phosphorylase	-
KZA74_RS16800 (KZA74_16810)	-	3537189..3538499 (-)	1311	WP_000753297.1	tetratricopeptide repeat protein	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 32094.47 Da
• Isoelectric Point: 7.1041

>NTDB_id=590314 KZA74_RS19675 WP_001152268.1 3533527..3534387(+) (pilD) [Acinetobacter baumannii strain 17978UN]
MQDIIAYFIQNFTALYIAVALVSLCIGSFLNVVIYRTPKMMEQDWQQECQMLLNPEQPIIDHEKLTLSKPASSCPACQQP
IRWYQNIPVISWLVLRGKCGHCQHPISIRYPAIELLTMLCSLVVVMVFGPTIQMLFGLVLTWVLIALTFIDFDTQLLPDR
FTLTLAALGLGINTFNIYTSPNSAIWGYLIGFLCLWIVYYLFKVITGKEGMGYGDFKLLAALGAWMGPLMLPLIVLLSSL
LGAIIGIILLKLRNDNQPFAFGPYIAIAGWVAFLWGDQIMKIYLGG

Nucleotide

• Length: 861 bp

>NTDB_id=590314 KZA74_RS19675 WP_001152268.1 3533527..3534387(+) (pilD) [Acinetobacter baumannii strain 17978UN]
ATGCAAGACATCATTGCGTATTTTATTCAAAACTTTACTGCACTTTATATTGCTGTTGCACTCGTGAGCCTATGTATCGG
TAGCTTTCTTAATGTAGTGATTTACCGCACGCCAAAAATGATGGAGCAAGATTGGCAGCAAGAATGCCAAATGCTGCTCA
ATCCTGAGCAACCCATTATTGATCATGAGAAGTTAACTTTAAGTAAGCCTGCTTCATCGTGCCCTGCATGTCAGCAACCG
ATCCGTTGGTATCAAAATATTCCTGTTATAAGCTGGCTTGTGTTAAGAGGAAAATGTGGTCATTGCCAGCACCCGATTAG
TATTCGCTATCCAGCCATCGAACTACTCACCATGCTATGTTCATTAGTAGTAGTCATGGTATTTGGCCCAACCATACAAA
TGCTTTTTGGACTCGTCCTCACATGGGTACTGATAGCCCTTACCTTTATTGATTTCGATACACAATTATTGCCTGATCGC
TTTACCCTAACTTTAGCTGCGCTCGGCTTAGGTATTAATACCTTTAATATTTATACCTCACCCAACTCAGCCATTTGGGG
TTATCTCATTGGTTTCCTATGTCTTTGGATTGTCTATTACTTATTTAAAGTGATCACTGGTAAAGAAGGTATGGGCTACG
GCGACTTTAAATTGCTTGCAGCATTAGGAGCATGGATGGGGCCATTGATGCTGCCGTTAATTGTGTTATTGTCATCGTTA
CTTGGCGCAATCATTGGCATCATTTTATTAAAATTAAGAAATGACAATCAGCCTTTTGCTTTTGGGCCATATATTGCCAT
TGCTGGTTGGGTTGCCTTTTTATGGGGTGATCAGATTATGAAAATTTATTTGGGAGGTTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (138-247)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (22-128)

3D structure

• AlphaFold DB: A0A1E3M8A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Acinetobacter baumannii D1279779	98.601	100	0.986
pilD	Acinetobacter nosocomialis M2	98.252	100	0.983
pilD	Vibrio cholerae strain A1552	53.875	94.755	0.51
pilD	Vibrio campbellii strain DS40M4	51.971	97.552	0.507
pilD	Neisseria gonorrhoeae MS11	47.348	92.308	0.437