Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   KZH43_RS06935 Genome accession   NZ_CP079923
Coordinates   1402887..1404119 (-) Length   410 a.a.
NCBI ID   WP_220041231.1    Uniprot ID   A0A2U3S138
Organism   Streptococcus pneumoniae strain Rx1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1397887..1409119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZH43_RS06905 (KZH43_06905) - 1398074..1399042 (+) 969 WP_000080996.1 NAD(P)/FAD-dependent oxidoreductase -
  KZH43_RS06910 (KZH43_06910) whiA 1399076..1399987 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  KZH43_RS06915 (KZH43_06915) - 1399984..1400961 (-) 978 WP_001231087.1 YvcK family protein -
  KZH43_RS06920 (KZH43_06920) rapZ 1400958..1401848 (-) 891 WP_000163025.1 RNase adapter RapZ -
  KZH43_RS06925 (KZH43_06925) - 1401900..1402280 (-) 381 WP_001140412.1 RidA family protein -
  KZH43_RS06930 (KZH43_06930) yihA 1402291..1402878 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  KZH43_RS06935 (KZH43_06935) clpX 1402887..1404119 (-) 1233 WP_220041231.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  KZH43_RS06940 (KZH43_06940) - 1404151..1404321 (-) 171 WP_000442275.1 hypothetical protein -
  KZH43_RS06945 (KZH43_06945) - 1404321..1404827 (-) 507 WP_000162439.1 dihydrofolate reductase -
  KZH43_RS06950 (KZH43_06950) - 1404957..1405475 (-) 519 WP_000229876.1 DNA starvation/stationary phase protection protein -
  KZH43_RS06955 (KZH43_06955) lytC 1405971..1407476 (-) 1506 WP_075825861.1 choline binding-anchored murein hydrolase LytC Auxiliary factor
  KZH43_RS06960 (KZH43_06960) tpiA 1407514..1408272 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  KZH43_RS06965 (KZH43_06965) - 1408370..1409047 (-) 678 WP_000221615.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45782.39 Da        Isoelectric Point: 4.4803

>NTDB_id=590183 KZH43_RS06935 WP_220041231.1 1402887..1404119(-) (clpX) [Streptococcus pneumoniae strain Rx1]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHVTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=590183 KZH43_RS06935 WP_220041231.1 1402887..1404119(-) (clpX) [Streptococcus pneumoniae strain Rx1]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGTTACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAGTACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U3S138

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561