Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   KX728_RS07685 Genome accession   NZ_CP079724
Coordinates   1568522..1569211 (-) Length   229 a.a.
NCBI ID   WP_000518005.1    Uniprot ID   A0A1X0WQD0
Organism   Streptococcus oralis strain 34     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1563522..1574211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS07660 (KX728_07655) - 1563583..1564590 (-) 1008 WP_215804357.1 phosphomevalonate kinase -
  KX728_RS07665 (KX728_07660) mvaD 1564577..1565530 (-) 954 WP_215804356.1 diphosphomevalonate decarboxylase -
  KX728_RS07670 (KX728_07665) mvk 1565512..1566390 (-) 879 WP_215804355.1 mevalonate kinase -
  KX728_RS07675 (KX728_07670) cbpC 1566508..1567527 (-) 1020 WP_215804354.1 N-acetylmuramoyl-L-alanine amidase family protein -
  KX728_RS07680 (KX728_07675) - 1567545..1568423 (-) 879 WP_215804353.1 N-acetylmuramoyl-L-alanine amidase family protein -
  KX728_RS07685 (KX728_07680) covR 1568522..1569211 (-) 690 WP_000518005.1 response regulator transcription factor Regulator
  KX728_RS07690 (KX728_07685) gndA 1569223..1570647 (-) 1425 WP_061587344.1 NADP-dependent phosphogluconate dehydrogenase -
  KX728_RS07695 (KX728_07690) - 1570723..1572168 (-) 1446 WP_215804352.1 cell division site-positioning protein MapZ family protein -
  KX728_RS07700 (KX728_07695) - 1572181..1573338 (-) 1158 WP_215804351.1 class I SAM-dependent RNA methyltransferase -
  KX728_RS07710 (KX728_07705) gpsB 1573824..1574153 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26827.00 Da        Isoelectric Point: 8.0271

>NTDB_id=588992 KX728_RS07685 WP_000518005.1 1568522..1569211(-) (covR) [Streptococcus oralis strain 34]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=588992 KX728_RS07685 WP_000518005.1 1568522..1569211(-) (covR) [Streptococcus oralis strain 34]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATTATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGGTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X0WQD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467