Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   KX728_RS02925 Genome accession   NZ_CP079724
Coordinates   564882..566114 (+) Length   410 a.a.
NCBI ID   WP_002874765.1    Uniprot ID   A0A1X1GRP7
Organism   Streptococcus oralis strain 34     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 559882..571114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS02890 (KX728_02885) galE 560554..561573 (+) 1020 WP_001156532.1 UDP-glucose 4-epimerase GalE -
  KX728_RS02895 (KX728_02890) - 561575..562540 (+) 966 WP_025171517.1 glycosyltransferase family 2 protein -
  KX728_RS02900 (KX728_02895) - 562616..562819 (-) 204 WP_002874767.1 ferredoxin -
  KX728_RS02905 (KX728_02900) - 562865..563371 (+) 507 WP_076984714.1 SAG1386/EF1546 family surface-associated protein -
  KX728_RS02910 (KX728_02905) cmk 563381..564055 (+) 675 WP_076984713.1 (d)CMP kinase -
  KX728_RS02915 (KX728_02910) - 564174..564680 (+) 507 WP_215804865.1 dihydrofolate reductase -
  KX728_RS02920 (KX728_02915) - 564680..564850 (+) 171 WP_000442252.1 hypothetical protein -
  KX728_RS02925 (KX728_02920) clpX 564882..566114 (+) 1233 WP_002874765.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  KX728_RS02930 (KX728_02925) yihA 566123..566710 (+) 588 WP_000405196.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  KX728_RS02935 (KX728_02930) - 566720..567100 (+) 381 WP_001140420.1 RidA family protein -
  KX728_RS02940 (KX728_02935) rapZ 567152..568042 (+) 891 WP_215804864.1 RNase adapter RapZ -
  KX728_RS02945 (KX728_02940) - 568039..569016 (+) 978 WP_042902709.1 YvcK family protein -
  KX728_RS02950 (KX728_02945) whiA 569013..569924 (+) 912 WP_049505290.1 DNA-binding protein WhiA -
  KX728_RS02955 (KX728_02950) - 569955..570923 (-) 969 WP_215804863.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45686.26 Da        Isoelectric Point: 4.4581

>NTDB_id=588969 KX728_RS02925 WP_002874765.1 564882..566114(+) (clpX) [Streptococcus oralis strain 34]
MPTNRKNDMMVYCSFCGKSQEEVKKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPIELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTEKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=588969 KX728_RS02925 WP_002874765.1 564882..566114(+) (clpX) [Streptococcus oralis strain 34]
ATGCCTACAAATAGGAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAGAGCCAAGAAGAAGTAAAGAAAATAAT
CGCTGGGAACAACGCCTTTATCTGTAATGAATGTGTGGAATTGGCCCAGGAAATCATTCGGGAGGAGTTGGCTGAGGAAG
TTTTGGCAGACTTGTCTGAAGTACCAAAACCAATCGAACTCCTCAATATCTTGAATCACTATGTGATCGGTCAGGATCGC
GCTAAACGTGCCTTGGCAGTGGCAGTTTACAACCACTACAAACGCATCAATTTCCATGATACTCGTGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGTCCAACTGGTTCTGGGAAAACCTTCTTGGCTCAGACTTTGGCTA
AGAGCTTGAACGTGCCTTTCGCTATTGCAGATGCGACAGCTCTGACTGAGGCTGGGTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTTTTGCAGGCTGCTGACTTTAACATCGAACGTGCAGAACGTGGGATTATCTACGTAGATGAAATTGA
CAAAATTGCCAAGAAGAGCGAGAATGTGTCTATCACACGTGACGTTTCGGGTGAAGGTGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTCGCTAGCGTGCCGCCTCAAGGAGGACGCAAACATCCACAACAAGAGATGATTCAGGTGGATACC
AAGAATATCCTCTTTATCGTGGGTGGTGCTTTTGATGGCATCGAAGAAATTGTGAAACAACGTCTGGGAGAAAAAGTTAT
CGGTTTCGGCCAAAATAACAAGGCAATTGACGAAAACAGCTCCTACATGCAAGAAATCATCGCAGAAGATATTCAAAAAT
TTGGGATTATCCCTGAGTTGATTGGACGTTTACCCGTCTTTGCAGCTCTTGAGCAATTGACGGTCGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAGGAAATCGCCAATAAGGCTATCGAACGCAAAACTGGTGCGCGTGGTCTTCGCTCAATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAAGTGCCAAGTCAGGAAAATGTGAAATTGGTTCGCATCACGAAAGAAGCTGTCGAT
GGAACGGAAAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GRP7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.073

100

0.871
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563