Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   KX728_RS01265 Genome accession   NZ_CP079724
Coordinates   235100..235924 (+) Length   274 a.a.
NCBI ID   WP_215805069.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 230100..240924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS01230 (KX728_01230) asnA 230190..231182 (+) 993 WP_084860344.1 aspartate--ammonia ligase -
  KX728_RS01235 (KX728_01235) rsmD 231247..231786 (+) 540 WP_215805073.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  KX728_RS01240 (KX728_01240) coaD 231776..232264 (+) 489 WP_215805072.1 pantetheine-phosphate adenylyltransferase -
  KX728_RS01245 (KX728_01245) sepM 232248..233285 (+) 1038 WP_215805071.1 SepM family pheromone-processing serine protease Regulator
  KX728_RS01250 (KX728_01250) - 233341..233571 (+) 231 WP_008276638.1 DUF1146 family protein -
  KX728_RS01255 (KX728_01255) murA 233595..234878 (+) 1284 WP_215805070.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  KX728_RS01260 (KX728_01260) - 234865..235059 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  KX728_RS01265 (KX728_01265) endA 235100..235924 (+) 825 WP_215805069.1 DNA/RNA non-specific endonuclease Machinery gene
  KX728_RS01270 (KX728_01270) - 236069..237400 (+) 1332 WP_061421650.1 hemolysin family protein -
  KX728_RS01280 (KX728_01280) amiA 237919..239898 (+) 1980 WP_215805068.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30043.72 Da        Isoelectric Point: 9.7188

>NTDB_id=588959 KX728_RS01265 WP_215805069.1 235100..235924(+) (endA) [Streptococcus oralis strain 34]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKISQKKQASEAPSQELAESVLTESIKNQIKGDLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGVYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=588959 KX728_RS01265 WP_215805069.1 235100..235924(+) (endA) [Streptococcus oralis strain 34]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTATATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACAAAGATTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTAG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAACCAAATCAAGGGTGATCTTGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCCAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAAAATCGTGAAGAAACAGGCAACGGCT
CAACCTCCTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAGTCTATACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGACGGTTTTGATGCCTCTACCAGCAACCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCCAACCAAGCTCAGGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AAAATAAGAGGGTTCGTTATCGCGTGACGCTCCACTATGCGACAAATGAGGACCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTAACGGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.377

99.635

0.891
  endA Streptococcus pneumoniae D39

89.377

99.635

0.891
  endA Streptococcus pneumoniae R6

89.377

99.635

0.891
  endA Streptococcus pneumoniae TIGR4

89.377

99.635

0.891