Detailed information NTG0588958

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: KX728_RS01245
• Genome accession: NZ_CP079724
• Coordinates: 232248..233285 (+)
• Length: 345 a.a.
• NCBI ID: WP_215805071.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain 34
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 227248..238285

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KX728_RS01210 (KX728_01210)	yidC	227283..228212 (-)	930	WP_215805098.1	membrane protein insertase YidC	-
KX728_RS01215 (KX728_01215)	-	228290..228568 (-)	279	WP_001174620.1	acylphosphatase	-
KX728_RS01220 (KX728_01220)	-	228602..229342 (+)	741	WP_215805074.1	RNA methyltransferase	-
KX728_RS01225 (KX728_01225)	-	229397..230080 (+)	684	WP_219108653.1	Bax inhibitor-1/YccA family protein	-
KX728_RS01230 (KX728_01230)	asnA	230190..231182 (+)	993	WP_084860344.1	aspartate--ammonia ligase	-
KX728_RS01235 (KX728_01235)	rsmD	231247..231786 (+)	540	WP_215805073.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
KX728_RS01240 (KX728_01240)	coaD	231776..232264 (+)	489	WP_215805072.1	pantetheine-phosphate adenylyltransferase	-
KX728_RS01245 (KX728_01245)	sepM	232248..233285 (+)	1038	WP_215805071.1	SepM family pheromone-processing serine protease	Regulator
KX728_RS01250 (KX728_01250)	-	233341..233571 (+)	231	WP_008276638.1	DUF1146 family protein	-
KX728_RS01255 (KX728_01255)	murA	233595..234878 (+)	1284	WP_215805070.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
KX728_RS01260 (KX728_01260)	-	234865..235059 (+)	195	WP_000739701.1	DNA-directed RNA polymerase subunit beta	-
KX728_RS01265 (KX728_01265)	endA	235100..235924 (+)	825	WP_215805069.1	DNA/RNA non-specific endonuclease	Machinery gene
KX728_RS01270 (KX728_01270)	-	236069..237400 (+)	1332	WP_061421650.1	hemolysin family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37548.76 Da
• Isoelectric Point: 5.8561

>NTDB_id=588958 KX728_RS01245 WP_215805071.1 232248..233285(+) (sepM) [Streptococcus oralis strain 34]
MKKKTRWPLYVILALVLTFLAFVVPLPYYIEVPGGAEDIRRVLKVNETEDTEAGAYQFVTVGIRHATLSHLVYAWLTPFT
DIRSAKETTGGSTDAEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
DSSKDLVDYVNSQQLGDTVKVTYEEDGKVKSAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRVVAGTGTIDRDGNVGDIGGIDKKVVAASRQGANIFFAPDNPVTEEAKKADPHAKSNYETALEAAK
TIKTEMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=588958 KX728_RS01245 WP_215805071.1 232248..233285(+) (sepM) [Streptococcus oralis strain 34]
ATGAAGAAAAAAACTAGATGGCCCTTATATGTCATCCTAGCACTAGTATTGACTTTTTTAGCCTTTGTAGTACCTTTACC
ATACTACATAGAAGTTCCAGGTGGAGCGGAAGATATTCGTAGAGTATTGAAAGTCAATGAAACAGAAGACACAGAAGCAG
GAGCTTACCAGTTTGTAACAGTCGGCATTCGACATGCAACTCTGTCGCATCTTGTCTATGCTTGGTTAACACCTTTCACG
GATATTAGAAGTGCCAAGGAGACTACGGGTGGCTCTACTGATGCAGAGTTTATGCGGATCAATCAGTTCTACATGCAAAC
TTCTCAAAATATGGCCAAGTATCAAGGACTGAAGACGGCTGGTAAGGATATCGAACTCAAGTACCTGGGAGTTTACGTTT
TAACCGTGACAGACAATTCGACTTTTAAAGGCATTCTGAACATTGCAGACACCGTGACGGCTGTTAATGACAAAACGTTT
GACAGTTCAAAAGACTTGGTCGACTATGTCAATTCTCAACAATTGGGGGACACGGTCAAGGTAACCTATGAAGAAGACGG
AAAAGTCAAGTCTGCTGAAGGTAAAATTATCACTCTCGAAAACGGGAAAAACGGGATTGGGATTGGTTTGATTGACCGTA
CAGAAGTGACCAGTGACGTTCCAATTCGCTTCTCCACAGCTGGTATCGGGGGACCAAGTGCTGGTCTTATGTTTAGTCTA
GCTATTTACACTCAGATAGCAGATCCAGGACTTCGTAATGGTCGCGTCGTTGCGGGAACGGGAACCATTGATCGCGATGG
AAATGTTGGAGACATCGGTGGAATTGACAAAAAAGTGGTTGCAGCCTCTCGTCAGGGAGCTAACATCTTTTTTGCTCCTG
ACAATCCAGTCACTGAGGAAGCAAAAAAAGCAGATCCACATGCGAAAAGCAACTATGAAACAGCCCTAGAAGCTGCTAAA
ACGATCAAAACAGAGATGAAAATCGTCCCTGTTAAGACCTTGCAGGATGCGATTGATTACCTTAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591