Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   M1B75_RS09615 Genome accession   NZ_CP096587
Coordinates   1958125..1958781 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC6622     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1953125..1963781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M1B75_RS09585 (M1B75_09585) dcyD 1954005..1954991 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  M1B75_RS09590 (M1B75_09590) tcyL 1955006..1955674 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  M1B75_RS09595 (M1B75_09595) tcyN 1955671..1956423 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  M1B75_RS09600 (M1B75_09600) sdiA 1956653..1957375 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  M1B75_RS09605 (M1B75_09605) yecF 1957442..1957666 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  M1B75_RS09610 (M1B75_09610) yecU 1957653..1957829 (-) 177 WP_000590347.1 protein YecU -
  M1B75_RS25455 - 1957912..1957983 (-) 72 Protein_1879 transcriptional regulator -
  M1B75_RS09615 (M1B75_09615) letA 1958125..1958781 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  M1B75_RS09620 (M1B75_09620) uvrC 1958778..1960610 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  M1B75_RS09625 (M1B75_09625) pgsA 1960667..1961215 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  M1B75_RS09645 (M1B75_09645) yecA 1961865..1962530 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=587181 M1B75_RS09615 WP_000611335.1 1958125..1958781(+) (letA) [Escherichia coli strain EC6622]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=587181 M1B75_RS09615 WP_000611335.1 1958125..1958781(+) (letA) [Escherichia coli strain EC6622]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486