Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   K747_RS03995 Genome accession   NC_021215
Coordinates   813572..814315 (+) Length   247 a.a.
NCBI ID   WP_015645815.1    Uniprot ID   -
Organism   Helicobacter pylori UM032     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 808572..819315
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K747_RS03970 (K747_04240) panD 810722..811072 (+) 351 WP_015645812.1 aspartate 1-decarboxylase -
  K747_RS03975 (K747_04245) - 811083..811376 (+) 294 WP_000347916.1 YbaB/EbfC family nucleoid-associated protein -
  K747_RS03980 (K747_04250) - 811376..812371 (+) 996 WP_015645813.1 PDZ domain-containing protein -
  K747_RS03985 (K747_04255) comB6 812379..813434 (+) 1056 WP_015645814.1 P-type conjugative transfer protein TrbL Machinery gene
  K747_RS03990 comB7 813450..813575 (+) 126 WP_020849792.1 hypothetical protein Machinery gene
  K747_RS03995 (K747_04260) comB8 813572..814315 (+) 744 WP_015645815.1 virB8 family protein Machinery gene
  K747_RS04000 (K747_04265) comB9 814315..815310 (+) 996 WP_015645816.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  K747_RS04005 (K747_04270) comB10 815303..816439 (+) 1137 WP_015645817.1 DNA type IV secretion system protein ComB10 Machinery gene
  K747_RS04010 (K747_04275) - 816505..817917 (+) 1413 WP_015645818.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  K747_RS04015 (K747_04280) gmd 817932..819077 (+) 1146 WP_015645819.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28726.99 Da        Isoelectric Point: 8.9546

>NTDB_id=58683 K747_RS03995 WP_015645815.1 813572..814315(+) (comB8) [Helicobacter pylori UM032]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=58683 K747_RS03995 WP_015645815.1 813572..814315(+) (comB8) [Helicobacter pylori UM032]
ATGAAGGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTATTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCTATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GTGCAAAGCCATTTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAGTTGGTATATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCAGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98

Multiple sequence alignment