Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   TL13_RS07655 Genome accession   NC_021213
Coordinates   1543239..1543928 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis TL13     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1538239..1548928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS07630 (TL13_1531) - 1539023..1540174 (-) 1152 WP_015647270.1 helicase DnaB -
  TL13_RS07635 (TL13_1532) nrdR 1540161..1540652 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  TL13_RS07640 (TL13_1533) - 1540724..1541854 (-) 1131 WP_002942701.1 AI-2E family transporter -
  TL13_RS07645 (TL13_1534) - 1542071..1542595 (-) 525 WP_015647271.1 hypothetical protein -
  TL13_RS07655 (TL13_1535) covR 1543239..1543928 (-) 690 WP_002942700.1 DNA-binding response regulator Regulator
  TL13_RS07660 (TL13_1536) gndA 1544010..1545437 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  TL13_RS07665 (TL13_1537) - 1545534..1546073 (-) 540 WP_014638519.1 YceD family protein -
  TL13_RS07670 (TL13_1538) trxB 1546083..1547000 (-) 918 WP_015647272.1 thioredoxin-disulfide reductase -
  TL13_RS07675 (TL13_1539) - 1547014..1547238 (-) 225 WP_002936682.1 DUF4059 family protein -
  TL13_RS07680 (TL13_1540) - 1547256..1548599 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=58640 TL13_RS07655 WP_002942700.1 1543239..1543928(-) (covR) [Streptococcus suis TL13]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=58640 TL13_RS07655 WP_002942700.1 1543239..1543928(-) (covR) [Streptococcus suis TL13]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACACGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment