Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   TL13_RS04945 Genome accession   NC_021213
Coordinates   991748..992974 (-) Length   408 a.a.
NCBI ID   WP_015646860.1    Uniprot ID   A0A0Z8EVL4
Organism   Streptococcus suis TL13     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 986748..997974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS04920 (TL13_0974) - 987068..988375 (-) 1308 WP_015646858.1 excalibur calcium-binding domain-containing protein -
  TL13_RS04925 (TL13_0975) - 988510..988692 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  TL13_RS04930 (TL13_0976) lepA 988742..990574 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  TL13_RS04935 (TL13_0977) ndk 990670..991083 (-) 414 WP_015646859.1 nucleoside-diphosphate kinase -
  TL13_RS04940 (TL13_0978) yihA 991106..991693 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  TL13_RS04945 (TL13_0979) clpX 991748..992974 (-) 1227 WP_015646860.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  TL13_RS04955 (TL13_0981) - 993172..993684 (-) 513 WP_015646861.1 dihydrofolate reductase -
  TL13_RS04960 (TL13_0982) - 994020..994859 (-) 840 WP_015646862.1 thymidylate synthase -
  TL13_RS04965 (TL13_0983) - 994912..995214 (-) 303 WP_012775088.1 hypothetical protein -
  TL13_RS04970 (TL13_0984) - 995226..995504 (-) 279 WP_012775087.1 hypothetical protein -
  TL13_RS04975 (TL13_0985) - 995630..996589 (-) 960 WP_015646863.1 ROK family glucokinase -
  TL13_RS04980 (TL13_0986) - 996685..997020 (-) 336 WP_015646864.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45309.83 Da        Isoelectric Point: 4.5987

>NTDB_id=58634 TL13_RS04945 WP_015646860.1 991748..992974(-) (clpX) [Streptococcus suis TL13]
MAVKHTQELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=58634 TL13_RS04945 WP_015646860.1 991748..992974(-) (clpX) [Streptococcus suis TL13]
ATGGCTGTTAAGCATACACAAGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAGGTTAAAAAAATTATCGC
AGGGAATAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACACCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTTCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATTGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTATCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTCTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8EVL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment