Detailed information NTG0586278

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: KV238_RS08920
• Genome accession: NZ_CP078012
• Coordinates: 1835763..1836992 (-)
• Length: 409 a.a.
• NCBI ID: WP_042670717.1
• Uniprot ID: A0A6M1KP89
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_18-036
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1830763..1841992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KV238_RS08910 (KV238_08895)	hupY	1831781..1834789 (-)	3009	WP_230923546.1	leucine-rich repeat adhesin HupY/LrrG	-
KV238_RS08915 (KV238_08900)	yihA	1835154..1835753 (-)	600	WP_230923547.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
KV238_RS08920 (KV238_08905)	clpX	1835763..1836992 (-)	1230	WP_042670717.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
KV238_RS08925 (KV238_08910)	-	1837028..1837198 (-)	171	WP_012515696.1	hypothetical protein	-
KV238_RS08930 (KV238_08915)	-	1837218..1837715 (-)	498	WP_021320814.1	dihydrofolate reductase	-
KV238_RS08935 (KV238_08920)	-	1837796..1838635 (-)	840	WP_043029774.1	thymidylate synthase	-
KV238_RS08940 (KV238_08925)	-	1838820..1839998 (+)	1179	WP_043053132.1	hydroxymethylglutaryl-CoA synthase	-
KV238_RS08945 (KV238_08930)	-	1839985..1841268 (+)	1284	WP_230923548.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45173.67 Da
• Isoelectric Point: 4.5698

>NTDB_id=586278 KV238_RS08920 WP_042670717.1 1835763..1836992(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLSDLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=586278 KV238_RS08920 WP_042670717.1 1835763..1836992(-) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAACAATGTCTTTATTTGTAATGAATGCGTTGCCTTGTCACAAGAAATCATCAAAGAAGAATTGGCAGAGGAGG
TTCTCTCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCGTTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGTAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGCTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGACGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCCATTACTCGTGATGTATCAGGAGAGGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTTGGAGGCGCTTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
TTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTGGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCCCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGGGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATTGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTCGAGGGT
CAATCAAAGCCCGTTTTAGAGATAGCCTAG

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

3D structure

• AlphaFold DB: A0A6M1KP89

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.509	100	0.885
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.352	98.044	0.582