Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   KV238_RS01010 Genome accession   NZ_CP078012
Coordinates   206371..207693 (-) Length   440 a.a.
NCBI ID   WP_115266677.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_18-036     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 201371..212693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KV238_RS01000 (KV238_00995) hpf 205107..205655 (-) 549 WP_230923705.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  KV238_RS01005 (KV238_01000) - 205731..206312 (-) 582 WP_230923706.1 ComF family protein -
  KV238_RS01010 (KV238_01005) comFA/cflA 206371..207693 (-) 1323 WP_115266677.1 DEAD/DEAH box helicase Machinery gene
  KV238_RS01015 (KV238_01010) - 207749..208390 (+) 642 WP_126436996.1 YigZ family protein -
  KV238_RS01020 (KV238_01015) cysK 208511..209437 (+) 927 WP_230923707.1 cysteine synthase A -
  KV238_RS01025 (KV238_01020) - 209824..210186 (-) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  KV238_RS01030 (KV238_01025) - 210186..211586 (-) 1401 WP_111692703.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  KV238_RS01035 (KV238_01030) - 211619..212260 (-) 642 WP_021321066.1 response regulator -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49983.10 Da        Isoelectric Point: 9.6948

>NTDB_id=586228 KV238_RS01010 WP_115266677.1 206371..207693(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
MENIENYYGRLFPEGKCPKAVSAWACSLQSMITKKGTLYCQRCGSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
APFPKAHYLRWQGQLTTYQAAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVNKGGWVCIASPRVDVCIELEKR
LSRDFSCQVCLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKTDAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRFITLVKKQRATGYPLLIFFPLIELAEQCCQL
LQKYFPKETIAHASSQSSNRMTIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISQAMLKAVREIKDMNQKGYQNELSTLPQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=586228 KV238_RS01010 WP_115266677.1 206371..207693(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain SEZ_18-036]
ATGGAGAATATCGAAAATTACTATGGACGCCTTTTCCCTGAAGGGAAATGCCCAAAGGCTGTTTCTGCCTGGGCTTGCAG
CTTACAAAGCATGATCACTAAAAAGGGAACGTTATACTGCCAACGCTGTGGCAGTTTAATTGAGAAGGCTCATCAGCTGC
CTAGCGGTGCTTACTACTGTAGAGCCTGTCTTGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTCCTTTTCCAAAGGCACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACCTTAGTTCATGCGGTTACTGGTGCTGGCAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTAATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTCTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAGTCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGTCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCTTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAACAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGATTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACATTGGCAAGAAGATTTCATGGCAAGCCCTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGGTTCATCACCCTAG
TCAAAAAACAAAGGGCAACTGGCTATCCTCTCTTAATCTTTTTTCCGCTTATTGAGCTGGCTGAGCAATGCTGTCAGCTG
CTCCAAAAGTATTTTCCTAAGGAAACTATTGCCCATGCTTCTAGTCAGTCATCAAATCGAATGACTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACCTTTCCGACCGTAGATGTCTTTG
TCTTATTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAAATTTCAGGTCGCGTTGGGCGCTCTTTGGAAAGA
CCGGAAGGACAGGTGCTATTTTTTCATGATGGTATTAGCCAGGCTATGCTCAAGGCAGTGCGGGAGATAAAGGACATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGCCACAATAA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(98-244)

Helicase conserved C-terminal domain (Helicase_C)

(288-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae D39

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae R6

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae Rx1

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae TIGR4

53.176

96.591

0.514
  comFA/cflA Streptococcus mitis NCTC 12261

52.941

96.591

0.511
  comFA Lactococcus lactis subsp. cremoris KW2

48.469

89.091

0.432