Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   MY487_RS08585 Genome accession   NZ_CP096033
Coordinates   1691853..1693727 (+) Length   624 a.a.
NCBI ID   WP_012117587.1    Uniprot ID   A7Z4X6
Organism   Bacillus amyloliquefaciens strain GL18     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1686853..1698727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MY487_RS08570 (MY487_08570) ymcA 1687904..1688335 (+) 432 WP_003154113.1 RicAFT regulatory complex protein RicA family protein Regulator
  MY487_RS08575 (MY487_08575) cotE 1688588..1689133 (+) 546 WP_003154111.1 outer spore coat protein CotE -
  MY487_RS08580 (MY487_08580) hexA 1689252..1691837 (+) 2586 WP_041482253.1 DNA mismatch repair protein MutS Machinery gene
  MY487_RS08585 (MY487_08585) hexB 1691853..1693727 (+) 1875 WP_012117587.1 DNA mismatch repair endonuclease MutL Machinery gene
  MY487_RS08590 (MY487_08590) - 1694121..1694330 (-) 210 WP_041482193.1 hypothetical protein -
  MY487_RS08595 (MY487_08595) - 1695295..1695972 (+) 678 WP_012117588.1 MBL fold metallo-hydrolase -
  MY487_RS08600 (MY487_08600) fabD 1696287..1697156 (+) 870 WP_012117589.1 ACP S-malonyltransferase -
  MY487_RS08605 (MY487_08605) - 1697293..1698267 (+) 975 WP_012117590.1 acyltransferase domain-containing protein -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 70144.41 Da        Isoelectric Point: 6.0176

>NTDB_id=585791 MY487_RS08585 WP_012117587.1 1691853..1693727(+) (hexB) [Bacillus amyloliquefaciens strain GL18]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDANSTVIEIDIEEAGLSSIRVLDNGEGMETDDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEIKTSIGEGAGTHLILQGGNIISEQKSSSRKGTEIIVTNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHQGKNLLQTNGNGDVRHVLAAIYGTAVAKKMIPLHISSLDFEVKGYIALPE
ITRASRNYMSSVINGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHELIRDG
IKEVFQKQRLIPSAQLPKKSAPAPAKNEQQFMTFEESAPERKLPEKTPEPSYSPMKLSSVVKEPEPVIIEEEILPNEADH
GVPPELGMPETAAPVSDTPEPEAVSEEIREERVPMMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGQVE
PEVQDMIVPLTFHYAANEALIIDQHQHELESVGVFLEAFGTNSYIVRCHPAWFPKGEEAELIEEIIQQVLDAKQIDIKKL
REEAAIMMSCKGSIKANRHLRNDEIKALLDDLRRTTDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=585791 MY487_RS08585 WP_012117587.1 1691853..1693727(+) (hexB) [Bacillus amyloliquefaciens strain GL18]
TTGGCAAAAGTCATCCAGCTGTCAGATGAACTCTCGAATAAAATAGCGGCCGGCGAGGTGGTCGAACGGCCTGCCTCAGT
CGTTAAAGAATTGGTGGAAAACGCCATCGACGCAAACAGCACAGTCATTGAAATCGACATAGAGGAAGCGGGGCTTTCGT
CGATTCGGGTGCTCGATAACGGCGAAGGGATGGAAACCGATGATTGCAAGCGGGCTTTCCGCCGCCACGCGACCAGTAAA
ATCAAAGATGAAAACGACCTGTTCCGGGTGAGAACACTCGGTTTCCGCGGAGAAGCTTTGCCAAGTATCGCGTCTGTTTC
TCATCTGGAAATCAAAACGAGCATCGGCGAGGGAGCGGGAACCCATCTCATTCTTCAGGGCGGGAATATCATTTCTGAGC
AGAAATCCTCCAGCAGAAAAGGAACGGAGATTATCGTTACCAACCTGTTTTTCAATACACCCGCCAGATTGAAATATATG
AAAACCGTGCATACGGAGCTCGGCAATATTACGGATGTTGTCAACCGGATCGCTCTTGCGCATCCGGAAGTATCCATCCG
TCTCCGCCATCAGGGGAAAAATCTGCTGCAGACAAACGGTAACGGGGACGTGCGCCATGTGCTGGCCGCAATTTACGGGA
CGGCGGTTGCGAAAAAAATGATACCGCTCCATATCAGCTCGCTTGATTTTGAAGTCAAGGGCTACATTGCGCTTCCGGAA
ATCACGCGTGCATCCAGAAACTACATGTCATCTGTCATTAACGGAAGATACATTAAGAATTTCCCGCTTGTAAAAGCAGT
GCATGAGGGCTATCACACACTTCTGCCGATCGGCCGCCATCCGATTACGTTTATCGAAATTACGATGGACCCGATTTTGG
TTGATGTCAATGTCCATCCGTCGAAGCTTGAAGTCCGCCTCAGCAAAGAGACAGAGCTGCATGAGCTGATCCGTGACGGG
ATAAAGGAAGTGTTTCAAAAGCAGCGGCTTATTCCGAGCGCCCAGCTCCCGAAAAAATCAGCGCCGGCACCGGCCAAAAA
CGAACAGCAATTTATGACATTCGAGGAAAGCGCGCCTGAGCGGAAACTTCCTGAAAAAACGCCGGAGCCGTCTTACTCAC
CAATGAAGCTGAGTTCGGTCGTAAAAGAGCCTGAGCCGGTAATAATAGAAGAAGAGATCCTCCCGAATGAAGCGGATCAC
GGAGTGCCGCCGGAGCTCGGTATGCCCGAAACGGCAGCGCCTGTTTCCGATACTCCGGAACCGGAAGCTGTCTCTGAAGA
AATACGGGAAGAAAGAGTTCCGATGATGTATCCGATCGGCCAAATGCACGGGACATATATTTTAGCTCAAAACGAAAACG
GCTTGTATATCATTGACCAGCATGCGGCCCAAGAACGGATTAAATACGAATATTTCCGGGAGAAGGTCGGGCAGGTTGAG
CCTGAAGTGCAGGATATGATCGTGCCGCTCACCTTTCATTATGCGGCAAATGAAGCGCTGATCATTGACCAGCATCAGCA
TGAGCTTGAAAGCGTCGGAGTATTTTTAGAAGCATTCGGCACGAACAGCTACATCGTTCGCTGCCATCCGGCCTGGTTTC
CAAAAGGGGAAGAAGCTGAACTGATTGAAGAAATCATTCAGCAGGTGCTTGACGCCAAACAGATCGATATTAAGAAACTG
CGGGAGGAAGCGGCCATTATGATGAGCTGCAAAGGCTCAATCAAAGCGAACCGCCATTTGCGAAACGACGAAATCAAAGC
GCTCTTGGACGACCTGCGCCGAACGACAGACCCGTTCACATGCCCGCACGGCCGGCCGATCATTATCCACCACAGTACGT
ATGAGATGGAGAAAATGTTTAAGCGTGTGATGTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(439-580)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A7Z4X6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.357

100

0.479