Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   KTR69_RS00315 Genome accession   NZ_CP077960
Coordinates   63438..64787 (-) Length   449 a.a.
NCBI ID   WP_129407195.1    Uniprot ID   -
Organism   Mammaliicoccus sciuri strain WHA07     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 53546..81261 63438..64787 within 0


Gene organization within MGE regions


Location: 53546..81261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KTR69_RS00255 - 53546..54283 (-) 738 Protein_48 tyrosine-type recombinase/integrase -
  KTR69_RS00260 cfr 54969..56018 (-) 1050 WP_001010505.1 23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr -
  KTR69_RS00265 - 56137..56316 (-) 180 WP_013356267.1 hypothetical protein -
  KTR69_RS00270 istB 56560..57312 (-) 753 WP_000358824.1 IS21-like element ISSau9 family helper ATPase IstB -
  KTR69_RS00275 istA 57305..58852 (-) 1548 WP_032495648.1 IS21 family transposase -
  KTR69_RS00280 - 58961..59398 (-) 438 Protein_53 site-specific integrase -
  KTR69_RS00285 - 59512..59838 (-) 327 WP_218697005.1 JAB domain-containing protein -
  KTR69_RS00290 - 59831..60037 (-) 207 WP_218697006.1 hypothetical protein -
  KTR69_RS00295 - 60039..60560 (-) 522 WP_218697007.1 DUF1643 domain-containing protein -
  KTR69_RS00300 - 60581..60889 (-) 309 WP_218697008.1 DUF960 family protein -
  KTR69_RS00305 - 60974..61324 (-) 351 WP_218697009.1 SAUGI family uracil-DNA glycosylase inhibitor -
  KTR69_RS00310 ccrB 61789..63417 (-) 1629 WP_218697010.1 cassette chromosome recombinase CcrB Machinery gene
  KTR69_RS00315 ccrA 63438..64787 (-) 1350 WP_129407195.1 cassette chromosome recombinase CcrA Machinery gene
  KTR69_RS00320 cch1 64966..66756 (-) 1791 WP_218697011.1 cassette chromosome replicative helicase -
  KTR69_RS00325 - 66882..68312 (-) 1431 WP_218697012.1 DUF6038 family protein -
  KTR69_RS00330 - 69061..70380 (+) 1320 WP_204183574.1 hypothetical protein -
  KTR69_RS00335 - 70381..72369 (+) 1989 WP_218697014.1 hypothetical protein -
  KTR69_RS00340 dfrG 72673..73170 (+) 498 WP_000868795.1 trimethoprim-resistant dihydrofolate reductase DfrG -
  KTR69_RS00345 - 73242..75194 (-) 1953 WP_000163792.1 hypothetical protein -
  KTR69_RS00350 - 75201..75437 (-) 237 WP_001159903.1 hypothetical protein -
  KTR69_RS00355 - 76035..77291 (+) 1257 WP_000566670.1 MrcB family domain-containing protein -
  KTR69_RS00360 - 77706..77945 (+) 240 WP_001282728.1 hypothetical protein -
  KTR69_RS00365 - 77977..78651 (-) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  KTR69_RS00370 - 78687..79076 (+) 390 WP_020444595.1 hydroxymethylglutaryl-CoA synthase -
  KTR69_RS00375 - 79993..80736 (+) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  KTR69_RS00380 - 80833..81261 (+) 429 WP_000872606.1 MaoC family dehydratase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52204.47 Da        Isoelectric Point: 10.1550

>NTDB_id=585689 KTR69_RS00315 WP_129407195.1 63438..64787(-) (ccrA) [Mammaliicoccus sciuri strain WHA07]
MKQAIGYLRQSTTKQQSLTAQKQTIQTLAKKYNIQYITFYSDKQSGKTDNRTGYQQVIERIQQKQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGLKEKARQGKLITTHAPFGYTYR
NGTFTINQNEAPTVKAIFHYYLQGYGYKKIAQYLEEDTKLINRKPYQVRNIIMNPNYCGRVNNKYGTFDNMFPSIISKAM
YKNAQAIRIKKQLHCIPSENQLKQKIKCPCCGSTLTNMTIRKTNHSLRYYVCPKNMNASRFICDFKGINAENLEKQVLES
CQKFFRDQQLYSKIKHAIEKQLKKQRMHDTSNTLTHEKLIEKLAQGTIDVETFREQSQSINLQNKPIQPISDIGIKASLQ
KVIQKSFTLNMLYPFIDVIHITKNKKLSGIYLKDEPLNIVNQAVQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=585689 KTR69_RS00315 WP_129407195.1 63438..64787(-) (ccrA) [Mammaliicoccus sciuri strain WHA07]
ATGAAACAAGCTATTGGTTATTTACGCCAAAGTACAACCAAGCAACAATCACTCACTGCACAGAAACAAACTATCCAAAC
ACTCGCTAAAAAATACAATATCCAATACATCACCTTTTATAGTGATAAGCAATCAGGCAAAACGGATAATCGAACAGGTT
ATCAACAAGTCATCGAACGCATTCAACAAAAACAATGTGACGTATTATGTTGTTATCGCTTAAATCGACTGCATCGTAAT
TTGAAAAATGCATTAAAACTTATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTTGATCGCCTAAAACTTAATATATTCATAAGTCTCGCAGAATTAGAGTCTGATAATATTGGTGAAC
AAGTCAAGAATGGCCTTAAAGAAAAAGCTAGACAAGGTAAACTCATCACGACACATGCACCATTTGGTTATACCTATCGC
AATGGTACATTCACAATTAATCAAAATGAAGCACCAACAGTTAAGGCAATATTCCATTACTACCTACAAGGTTATGGTTA
TAAAAAAATTGCGCAATACCTAGAAGAAGATACTAAGCTAATCAACCGAAAACCCTATCAAGTACGTAACATTATTATGA
ACCCTAATTACTGTGGACGTGTGAATAACAAATACGGTACTTTTGATAATATGTTCCCATCTATTATCAGTAAAGCAATG
TATAAAAATGCTCAAGCAATTCGTATTAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAAATAAA
ATGTCCTTGTTGTGGTTCAACCCTTACCAACATGACCATTAGAAAAACCAATCATTCATTACGTTATTATGTCTGTCCTA
AAAACATGAATGCATCACGTTTCATATGTGACTTTAAAGGCATAAACGCTGAAAACCTAGAAAAACAGGTCTTAGAATCT
TGCCAAAAATTCTTTCGAGACCAACAGCTCTATTCGAAAATCAAACATGCTATTGAGAAACAGCTCAAAAAACAAAGGAT
GCATGATACTAGTAACACATTAACTCATGAAAAGCTCATTGAAAAATTAGCACAAGGAACAATTGATGTAGAAACATTCA
GAGAACAATCTCAATCAATAAACCTACAGAATAAGCCTATACAACCAATAAGTGATATTGGGATAAAAGCATCGCTACAA
AAAGTTATACAGAAAAGTTTCACGTTAAACATGTTATATCCCTTTATTGATGTCATTCATATTACTAAAAATAAAAAACT
AAGCGGCATCTATTTAAAAGATGAGCCACTAAACATTGTTAATCAAGCGGTACAATCATCGATTGCTTAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

75.056

100

0.751
  ccrA Staphylococcus aureus N315

71.047

100

0.71