Detailed information NTG0585688

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: KTR69_RS00310
• Genome accession: NZ_CP077960
• Coordinates: 61789..63417 (-)
• Length: 542 a.a.
• NCBI ID: WP_218697010.1
• Uniprot ID: -
• Organism: Mammaliicoccus sciuri strain WHA07
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	53546..81261	61789..63417	within	0

Gene organization within MGE regions

Location: 53546..81261

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KTR69_RS00255	-	53546..54283 (-)	738	Protein_48	tyrosine-type recombinase/integrase	-
KTR69_RS00260	cfr	54969..56018 (-)	1050	WP_001010505.1	23S rRNA (adenine(2503)-C(8))-methyltransferase Cfr	-
KTR69_RS00265	-	56137..56316 (-)	180	WP_013356267.1	hypothetical protein	-
KTR69_RS00270	istB	56560..57312 (-)	753	WP_000358824.1	IS21-like element ISSau9 family helper ATPase IstB	-
KTR69_RS00275	istA	57305..58852 (-)	1548	WP_032495648.1	IS21 family transposase	-
KTR69_RS00280	-	58961..59398 (-)	438	Protein_53	site-specific integrase	-
KTR69_RS00285	-	59512..59838 (-)	327	WP_218697005.1	JAB domain-containing protein	-
KTR69_RS00290	-	59831..60037 (-)	207	WP_218697006.1	hypothetical protein	-
KTR69_RS00295	-	60039..60560 (-)	522	WP_218697007.1	DUF1643 domain-containing protein	-
KTR69_RS00300	-	60581..60889 (-)	309	WP_218697008.1	DUF960 family protein	-
KTR69_RS00305	-	60974..61324 (-)	351	WP_218697009.1	SAUGI family uracil-DNA glycosylase inhibitor	-
KTR69_RS00310	ccrB	61789..63417 (-)	1629	WP_218697010.1	cassette chromosome recombinase CcrB	Machinery gene
KTR69_RS00315	ccrA	63438..64787 (-)	1350	WP_129407195.1	cassette chromosome recombinase CcrA	Machinery gene
KTR69_RS00320	cch1	64966..66756 (-)	1791	WP_218697011.1	cassette chromosome replicative helicase	-
KTR69_RS00325	-	66882..68312 (-)	1431	WP_218697012.1	DUF6038 family protein	-
KTR69_RS00330	-	69061..70380 (+)	1320	WP_204183574.1	hypothetical protein	-
KTR69_RS00335	-	70381..72369 (+)	1989	WP_218697014.1	hypothetical protein	-
KTR69_RS00340	dfrG	72673..73170 (+)	498	WP_000868795.1	trimethoprim-resistant dihydrofolate reductase DfrG	-
KTR69_RS00345	-	73242..75194 (-)	1953	WP_000163792.1	hypothetical protein	-
KTR69_RS00350	-	75201..75437 (-)	237	WP_001159903.1	hypothetical protein	-
KTR69_RS00355	-	76035..77291 (+)	1257	WP_000566670.1	MrcB family domain-containing protein	-
KTR69_RS00360	-	77706..77945 (+)	240	WP_001282728.1	hypothetical protein	-
KTR69_RS00365	-	77977..78651 (-)	675	WP_001106057.1	IS6-like element IS257 family transposase	-
KTR69_RS00370	-	78687..79076 (+)	390	WP_020444595.1	hydroxymethylglutaryl-CoA synthase	-
KTR69_RS00375	-	79993..80736 (+)	744	WP_000958858.1	glycerophosphoryl diester phosphodiesterase	-
KTR69_RS00380	-	80833..81261 (+)	429	WP_000872606.1	MaoC family dehydratase	-

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62834.82 Da
• Isoelectric Point: 9.6733

>NTDB_id=585688 KTR69_RS00310 WP_218697010.1 61789..63417(-) (ccrB) [Mammaliicoccus sciuri strain WHA07]
MQQLKQKRVGIYVRVSTEMQSSEGYSIDGQINQIREYCQFHHFEVTDIYADRGISGKSMNRPELQRMLKDANEGHIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNIEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDNKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSINSITYILVNPFYIGKIQFAK
YKDWNEKRRKGLNEKPIIADGKHPPIISQELWDKVQSRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EIHAKLDNLIKTIEDNPDLTTILKETIHKYETQLNDIRNQINQLKQQQNQEKPSYDTKQISAILRRIFQNVESMNKSQLK
ALYLTVIDHIEIRKDSNRKKQFYVTLMLNNEIIKQLFNNNPLDEVLLSTSSLFLPQTIYLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=585688 KTR69_RS00310 WP_218697010.1 61789..63417(-) (ccrB) [Mammaliicoccus sciuri strain WHA07]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATGCAAAGTTCAGAAGGTTATAGTAT
TGATGGCCAAATCAATCAGATTAGAGAATACTGTCAATTTCATCATTTTGAAGTCACAGATATTTACGCTGATCGTGGTA
TCTCAGGAAAATCAATGAACCGCCCTGAGCTCCAACGTATGTTGAAGGATGCGAATGAAGGTCATATCGATTGTGTCATG
GTGTATAAAACAAACCGACTAGCACGTAATACATCAGACTTACTCAAAATTGTCGAAGATTTGCATAAACAAAATATTGA
ATTTTTCAGTCTATCTGAACGCATGGAAGTTAATACAAGTAGTGGTAAACTGATGCTACAAATACTTGCGAGCTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTCATGGGCCAAACTAGACGTGCACAAGAAGGCTATTATCAAGGAAAT
TTACCACTAGGATATGACAAAATACCTGATAATAAACACGAACTGATGATTAATCAACATGAAGCGAATATCGTGAAATA
TATATTCGAATCTTATGCCAAAGGACATGGTTATCGTAAAATTGCCAATGCCCTCAATCACAAAGGATATGTTACTAAAA
AAGGTAATCCTTTTAGCATCAATTCAATAACCTATATCTTAGTCAATCCATTCTACATTGGTAAAATTCAATTTGCGAAA
TATAAAGATTGGAATGAAAAGCGTCGTAAAGGACTGAATGAAAAACCTATTATAGCTGATGGTAAACACCCTCCTATTAT
TAGTCAAGAATTATGGGATAAAGTCCAATCACGCAAAAAACAGGTCAGTCAAAAACCTCAAGTTCATGGAAAAGGAACCA
ATCTATTAACGGGTATTATTCACTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACTAAGAAGCGAATACGTTATTATTCTTGTAGTAATTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGTGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAGAATAAAGTCGATATTGGTGCATTGAACCATGATATCGCTTATAAACAACAACAATACGAT
GAAATCCATGCGAAACTAGACAACTTGATTAAAACAATCGAAGATAATCCAGACTTAACAACAATACTCAAAGAAACAAT
CCATAAATATGAAACACAACTCAATGACATTAGGAATCAAATTAATCAACTTAAACAACAACAAAATCAAGAGAAACCAT
CATACGATACTAAACAAATATCTGCTATTTTACGTCGCATATTTCAAAACGTAGAATCAATGAATAAATCGCAACTCAAA
GCATTGTACCTTACAGTCATTGACCATATTGAGATTCGGAAAGATAGTAATCGTAAAAAGCAATTCTATGTCACACTCAT
GCTCAATAATGAAATTATCAAACAACTTTTCAATAATAACCCTCTAGACGAAGTGTTACTCAGCACTTCGTCTTTATTTT
TACCTCAAACCATTTATCTTCAAATATAG

Domains

Predicted by InterproScan.

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	85.793	100	0.858