Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   KVP03_RS07055 Genome accession   NZ_CP077959
Coordinates   1485379..1486608 (+) Length   409 a.a.
NCBI ID   WP_012677889.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_14-145     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1454732..1500585 1485379..1486608 within 0


Gene organization within MGE regions


Location: 1454732..1500585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVP03_RS06920 (KVP03_06905) - 1454732..1455331 (+) 600 WP_230923000.1 glycoside hydrolase family 73 protein -
  KVP03_RS06925 (KVP03_06910) - 1455893..1456102 (+) 210 WP_012515721.1 helix-turn-helix transcriptional regulator -
  KVP03_RS06930 (KVP03_06915) - 1456092..1456484 (+) 393 WP_021320833.1 hypothetical protein -
  KVP03_RS06935 (KVP03_06920) - 1456946..1457176 (+) 231 WP_014622960.1 hypothetical protein -
  KVP03_RS06940 - 1457258..1457470 (+) 213 Protein_1319 conjugal transfer protein TraA -
  KVP03_RS06945 (KVP03_06925) - 1457584..1458942 (+) 1359 WP_230923001.1 SLC13 family permease -
  KVP03_RS06950 (KVP03_06930) - 1459389..1460102 (+) 714 WP_230923002.1 glycoside hydrolase family 73 protein -
  KVP03_RS06955 (KVP03_06935) - 1460330..1460710 (+) 381 WP_012677870.1 DUF1149 family protein -
  KVP03_RS06960 (KVP03_06940) - 1460710..1461558 (+) 849 WP_012679645.1 DegV family protein -
  KVP03_RS06965 (KVP03_06945) - 1461658..1462869 (+) 1212 WP_043029790.1 CCA tRNA nucleotidyltransferase -
  KVP03_RS06970 (KVP03_06950) - 1462862..1464730 (+) 1869 WP_230923003.1 ABC-F family ATP-binding cassette domain-containing protein -
  KVP03_RS06975 (KVP03_06955) - 1464835..1466580 (+) 1746 WP_012677874.1 ABC transporter ATP-binding protein -
  KVP03_RS06980 (KVP03_06960) - 1466580..1468352 (+) 1773 WP_111678181.1 ABC transporter ATP-binding protein -
  KVP03_RS06985 (KVP03_06965) gdhA 1468493..1469842 (+) 1350 WP_230923004.1 NADP-specific glutamate dehydrogenase -
  KVP03_RS06990 (KVP03_06970) - 1469974..1470384 (+) 411 WP_012677877.1 peptide deformylase -
  KVP03_RS06995 (KVP03_06975) - 1470577..1472583 (-) 2007 WP_230923005.1 surface-anchored 5'-nucleotidase -
  KVP03_RS07000 (KVP03_06980) - 1473031..1474752 (+) 1722 WP_230923296.1 ABC transporter ATP-binding protein -
  KVP03_RS07005 (KVP03_06985) - 1474754..1476505 (+) 1752 WP_111678177.1 ABC transporter ATP-binding protein -
  KVP03_RS07010 (KVP03_06990) mvk 1477041..1477919 (+) 879 WP_111692493.1 mevalonate kinase -
  KVP03_RS07015 (KVP03_06995) mvaD 1477901..1478845 (+) 945 WP_111692492.1 diphosphomevalonate decarboxylase -
  KVP03_RS07020 (KVP03_07000) - 1478838..1479836 (+) 999 WP_111690156.1 phosphomevalonate kinase -
  KVP03_RS07025 (KVP03_07005) fni 1479839..1480831 (+) 993 WP_230923006.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  KVP03_RS07030 (KVP03_07010) - 1481106..1482389 (-) 1284 WP_206158030.1 hydroxymethylglutaryl-CoA reductase, degradative -
  KVP03_RS07035 (KVP03_07015) - 1482376..1483551 (-) 1176 WP_230923007.1 hydroxymethylglutaryl-CoA synthase -
  KVP03_RS07040 (KVP03_07020) - 1483736..1484575 (+) 840 WP_043025902.1 thymidylate synthase -
  KVP03_RS07045 (KVP03_07025) - 1484656..1485153 (+) 498 WP_111692489.1 dihydrofolate reductase -
  KVP03_RS07050 (KVP03_07030) - 1485173..1485343 (+) 171 WP_012515696.1 hypothetical protein -
  KVP03_RS07055 (KVP03_07035) clpX 1485379..1486608 (+) 1230 WP_012677889.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  KVP03_RS07060 (KVP03_07040) yihA 1486618..1487217 (+) 600 WP_111692488.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  KVP03_RS07065 (KVP03_07045) hupY 1487590..1490592 (+) 3003 WP_154299001.1 leucine-rich repeat adhesin HupY/LrrG -
  KVP03_RS07070 (KVP03_07050) clpC 1490782..1492875 (-) 2094 WP_230923008.1 AAA family ATPase Regulator
  KVP03_RS07075 (KVP03_07055) ndk 1493246..1493665 (+) 420 WP_012515690.1 nucleoside-diphosphate kinase -
  KVP03_RS07080 (KVP03_07060) - 1494165..1494971 (+) 807 WP_126436747.1 DNA/RNA non-specific endonuclease -
  KVP03_RS07085 (KVP03_07065) - 1495256..1496221 (-) 966 WP_230923009.1 polysaccharide deacetylase family protein -
  KVP03_RS07090 (KVP03_07070) - 1496393..1497676 (+) 1284 WP_111692482.1 homoserine dehydrogenase -
  KVP03_RS07095 (KVP03_07075) thrB 1497678..1498538 (+) 861 WP_037581040.1 homoserine kinase -
  KVP03_RS07100 (KVP03_07080) - 1498703..1499962 (+) 1260 WP_111692481.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  KVP03_RS07105 (KVP03_07085) folE 1500019..1500585 (+) 567 WP_308733129.1 GTP cyclohydrolase I FolE -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45197.77 Da        Isoelectric Point: 4.5726

>NTDB_id=585664 KVP03_RS07055 WP_012677889.1 1485379..1486608(+) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVRITKEAVEG
QSKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=585664 KVP03_RS07055 WP_012677889.1 1485379..1486608(+) (clpX) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGTAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTGCTTGAGATTTTAAATCAATACGTCATTGGGCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTACAACCACTACAAGAGGATTTCATTTACTGAGAGTCGTGATGATGATGATGT
GGATTTGCAGAAGTCCAATATTCTGATGATTGGACCAACAGGCTCAGGAAAGACCTTTTTGGCACAGACCCTGGCTAAGA
GTCTGAATGTTCCGTTTGCTATTGCTGATGCAACCTCTTTGACTGAGGCAGGCTATGTCGGAGAAGATGTGGAAAATATC
CTCCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAGCGTGCAGAGCGCGGCATTATTTATGTTGACGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAAGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCCTTTGATGGTATCGAAGAAATTGTCAAGCAGCGCTTGGGAGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCTTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTGGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCCCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGGGCTCTGGAGGCTATTGCAGGTAGGGCTATTGAGCGCAAGACTGGTGCGCGTGGTCTGAGGTCTATTATTGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAATCAAGGTACGCATTACTAAGGAAGCTGTCGAAGGT
CAATCAAAGCCTATTTTAGAGATAGCCTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.888
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577