Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   KU512_RS11695 Genome accession   NZ_CP077933
Coordinates   2293192..2294541 (-) Length   449 a.a.
NCBI ID   WP_061657934.1    Uniprot ID   M1XI66
Organism   Staphylococcus aureus strain 359     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2288192..2299541
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU512_RS14570 - 2288269..2288448 (+) 180 Protein_2268 restriction endonuclease subunit S -
  KU512_RS14575 - 2288710..2288845 (+) 136 Protein_2269 restriction endonuclease subunit S -
  KU512_RS14580 - 2289088..2289462 (+) 375 Protein_2270 restriction endonuclease subunit S -
  KU512_RS11670 (KU512_11665) - 2289568..2289791 (-) 224 Protein_2271 hypothetical protein -
  KU512_RS11675 (KU512_11670) - 2289805..2290314 (-) 510 WP_031903864.1 DUF1643 domain-containing protein -
  KU512_RS11680 (KU512_11675) - 2290329..2290640 (-) 312 WP_031903865.1 DUF960 family protein -
  KU512_RS11685 (KU512_11680) - 2290727..2291077 (-) 351 WP_031903866.1 SAUGI family uracil-DNA glycosylase inhibitor -
  KU512_RS11690 (KU512_11685) ccrB 2291543..2293171 (-) 1629 WP_061657937.1 cassette chromosome recombinase CcrB Machinery gene
  KU512_RS11695 (KU512_11690) ccrA 2293192..2294541 (-) 1350 WP_061657934.1 cassette chromosome recombinase CcrA Machinery gene
  KU512_RS11700 (KU512_11695) cch1 2294729..2296498 (-) 1770 WP_000020211.1 cassette chromosome replicative helicase -
  KU512_RS11705 (KU512_11700) ssb 2296498..2296794 (-) 297 WP_000220590.1 cassette chromosome ssDNA-binding protein -
  KU512_RS11710 (KU512_11705) - 2296967..2298481 (-) 1515 WP_061657932.1 hypothetical protein -
  KU512_RS11715 (KU512_11710) - 2298621..2299325 (+) 705 WP_016170663.1 FRG domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52426.82 Da        Isoelectric Point: 9.8746

>NTDB_id=585558 KU512_RS11695 WP_061657934.1 2293192..2294541(-) (ccrA) [Staphylococcus aureus strain 359]
MKQAIGYLRQSTTKQQSLAAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQTYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDNFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKSDHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIETKTTLNHEQLIEKLAQGKIDADTFREQSQSFRQQSNPITSINAHQIRKVFQ
NIIQQRFTLNMLYPYIDEIHITKNKTLTGIYFKNEPLNIVNQTAQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=585558 KU512_RS11695 WP_061657934.1 2293192..2294541(-) (ccrA) [Staphylococcus aureus strain 359]
ATGAAACAAGCAATAGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCAAGGC
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAGCTCATGAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAGACAAGGTAAACTAATTACAACACATGCTCCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAGTCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAACTTCATTAATCGCAAGCCTTATCAAGTGCGTAATATTATCCTCA
ACCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTAAAACGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGTCATTCGACACTCACAAACATGACTGTCCGCAAATCAGATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAATCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGATACGTTCA
GAGAACAATCGCAATCATTTCGACAACAGTCAAACCCTATAACATCAATCAATGCACATCAAATTCGAAAGGTTTTTCAA
AATATCATACAACAACGTTTCACGTTAAACATGTTGTACCCTTACATTGATGAAATTCATATTACCAAAAATAAAACACT
TACGGGTATCTATTTCAAAAATGAGCCCTTAAACATCGTCAATCAAACGGCGCAATCATCGATTGCTTAA

Domains

Predicted by InterProScan.

Recombinase (Recombinase)

(170-249)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

92.205

100

0.922
  ccrA Staphylococcus aureus N315

76.392

100

0.764