Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU512_RS01185 Genome accession   NZ_CP077933
Coordinates   219802..220371 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 359     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 214802..225371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU512_RS01160 (KU512_01160) cysE 216015..216662 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KU512_RS01165 (KU512_01165) cysS 216646..218046 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  KU512_RS01170 (KU512_01170) - 218039..218443 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  KU512_RS01175 (KU512_01175) rlmB 218451..219197 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU512_RS01180 (KU512_01180) - 219197..219721 (+) 525 WP_000664738.1 NYN domain-containing protein -
  KU512_RS01185 (KU512_01185) sigH 219802..220371 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU512_RS01190 (KU512_01190) rpmG 220486..220629 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU512_RS01195 (KU512_01195) secE 220685..220867 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU512_RS01200 (KU512_01200) nusG 220880..221428 (+) 549 WP_050956556.1 transcription termination/antitermination protein NusG -
  KU512_RS01205 (KU512_01205) rplK 221609..222031 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU512_RS01210 (KU512_01210) rplA 222239..222931 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU512_RS01215 (KU512_01215) rplJ 223203..223703 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU512_RS01220 (KU512_01220) rplL 223746..224114 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU512_RS01225 (KU512_01225) - 224289..224897 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=585526 KU512_RS01185 WP_000872873.1 219802..220371(+) (sigH) [Staphylococcus aureus strain 359]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=585526 KU512_RS01185 WP_000872873.1 219802..220371(+) (sigH) [Staphylococcus aureus strain 359]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984