Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU504_RS00135 Genome accession   NZ_CP077926
Coordinates   29088..29657 (-) Length   189 a.a.
NCBI ID   WP_000872878.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 197     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 24088..34657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU504_RS00095 (KU504_00095) - 24562..25170 (-) 609 WP_000020295.1 class I SAM-dependent methyltransferase -
  KU504_RS00100 (KU504_00100) rplL 25345..25713 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU504_RS00105 (KU504_00105) rplJ 25756..26256 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU504_RS00110 (KU504_00110) rplA 26528..27220 (-) 693 WP_225798374.1 50S ribosomal protein L1 -
  KU504_RS00115 (KU504_00115) rplK 27428..27850 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU504_RS00120 (KU504_00120) nusG 28031..28579 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU504_RS00125 (KU504_00125) secE 28592..28774 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU504_RS00130 (KU504_00130) rpmG 28830..28973 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU504_RS00135 (KU504_00135) sigH 29088..29657 (-) 570 WP_000872878.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU504_RS00140 (KU504_00140) - 29738..30262 (-) 525 WP_000664731.1 NYN domain-containing protein -
  KU504_RS00145 (KU504_00145) rlmB 30262..31008 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU504_RS00150 (KU504_00150) - 31016..31420 (-) 405 WP_000370179.1 Mini-ribonuclease 3 -
  KU504_RS00155 (KU504_00155) cysS 31413..32813 (-) 1401 WP_000631980.1 cysteine--tRNA ligase -
  KU504_RS00160 (KU504_00160) cysE 32797..33444 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=585355 KU504_RS00135 WP_000872878.1 29088..29657(-) (sigH) [Staphylococcus aureus strain 197]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCVIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=585355 KU504_RS00135 WP_000872878.1 29088..29657(-) (sigH) [Staphylococcus aureus strain 197]
TTGAAATATGATTTGACAACTCAAGATAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGTAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979