Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MYG04_RS05195 Genome accession   NZ_CP095856
Coordinates   1030857..1031513 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain EC6563     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1025857..1036513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYG04_RS05165 (MYG04_05165) yecA 1027109..1027774 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  MYG04_RS05185 (MYG04_05185) pgsA 1028423..1028971 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYG04_RS05190 (MYG04_05190) uvrC 1029028..1030860 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  MYG04_RS05195 (MYG04_05195) letA 1030857..1031513 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYG04_RS25775 - 1031655..1031771 (+) 117 WP_001302039.1 hypothetical protein -
  MYG04_RS05200 (MYG04_05200) yecU 1031809..1031985 (+) 177 WP_000590344.1 protein YecU -
  MYG04_RS05205 (MYG04_05205) yecF 1031972..1032196 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYG04_RS05210 (MYG04_05210) sdiA 1032264..1032986 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  MYG04_RS05215 (MYG04_05215) tcyN 1033216..1033968 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYG04_RS05220 (MYG04_05220) tcyL 1033965..1034633 (-) 669 WP_108429899.1 cystine ABC transporter permease -
  MYG04_RS05225 (MYG04_05225) dcyD 1034648..1035634 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=585271 MYG04_RS05195 WP_000611328.1 1030857..1031513(-) (letA) [Escherichia coli strain EC6563]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=585271 MYG04_RS05195 WP_000611328.1 1030857..1031513(-) (letA) [Escherichia coli strain EC6563]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482