Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU538_RS13260 Genome accession   NZ_CP077922
Coordinates   2694015..2694584 (+) Length   189 a.a.
NCBI ID   WP_000872879.1    Uniprot ID   A0A2S6DF07
Organism   Staphylococcus aureus strain 202     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2689015..2699584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU538_RS13235 (KU538_13145) cysE 2690227..2690874 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KU538_RS13240 (KU538_13150) cysS 2690858..2692258 (+) 1401 WP_000631961.1 cysteine--tRNA ligase -
  KU538_RS13245 (KU538_13155) - 2692251..2692655 (+) 405 WP_000370181.1 Mini-ribonuclease 3 -
  KU538_RS13250 (KU538_13160) rlmB 2692663..2693409 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU538_RS13255 (KU538_13165) - 2693409..2693933 (+) 525 WP_000664738.1 NYN domain-containing protein -
  KU538_RS13260 (KU538_13170) sigH 2694015..2694584 (+) 570 WP_000872879.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU538_RS13265 (KU538_13175) rpmG 2694699..2694842 (+) 144 WP_225805668.1 50S ribosomal protein L33 -
  KU538_RS13270 (KU538_13180) secE 2694898..2695080 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU538_RS13275 (KU538_13185) nusG 2695093..2695641 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU538_RS13280 (KU538_13190) rplK 2695822..2696244 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU538_RS13285 (KU538_13195) rplA 2696452..2697144 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU538_RS13290 (KU538_13200) rplJ 2697416..2697916 (+) 501 WP_001273088.1 50S ribosomal protein L10 -
  KU538_RS13295 (KU538_13205) rplL 2697959..2698327 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU538_RS13300 (KU538_13210) - 2698502..2699110 (+) 609 WP_225805669.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.02 Da        Isoelectric Point: 9.7681

>NTDB_id=585229 KU538_RS13260 WP_000872879.1 2694015..2694584(+) (sigH) [Staphylococcus aureus strain 202]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGKQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=585229 KU538_RS13260 WP_000872879.1 2694015..2694584(+) (sigH) [Staphylococcus aureus strain 202]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAAAGCAGCCTTTCACAAATTATGTTCAGTGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6DF07

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979