Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   MYL27_RS14390 Genome accession   NZ_CP095836
Coordinates   2888464..2890296 (-) Length   610 a.a.
NCBI ID   WP_001283427.1    Uniprot ID   -
Organism   Escherichia coli strain EC31     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2883464..2895296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL27_RS14345 (MYL27_14265) - 2883473..2883940 (-) 468 WP_000824288.1 TIR domain-containing protein -
  MYL27_RS14350 (MYL27_14270) - 2883943..2885388 (-) 1446 WP_033544572.1 SIR2 family protein -
  MYL27_RS14355 (MYL27_14275) - 2885802..2886062 (+) 261 WP_000488111.1 ogr/Delta-like zinc finger family protein -
  MYL27_RS14360 (MYL27_14280) - 2886254..2886394 (+) 141 WP_000078916.1 Hok/Gef family protein -
  MYL27_RS14365 (MYL27_14285) - 2886584..2886865 (-) 282 WP_071527557.1 hypothetical protein -
  MYL27_RS14385 (MYL27_14305) pgsA 2887859..2888407 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYL27_RS14390 (MYL27_14310) uvrC 2888464..2890296 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  MYL27_RS14395 (MYL27_14315) letA 2890293..2890949 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYL27_RS14400 - 2891091..2891207 (+) 117 WP_001302039.1 hypothetical protein -
  MYL27_RS14405 (MYL27_14320) yecU 2891245..2891421 (+) 177 WP_000590344.1 protein YecU -
  MYL27_RS14410 (MYL27_14325) yecF 2891408..2891632 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYL27_RS14415 (MYL27_14330) sdiA 2891699..2892421 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  MYL27_RS14420 (MYL27_14335) tcyN 2892651..2893403 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYL27_RS14425 (MYL27_14340) tcyL 2893400..2894068 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MYL27_RS14430 (MYL27_14345) dcyD 2894083..2895069 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68202.06 Da        Isoelectric Point: 9.3685

>NTDB_id=585219 MYL27_RS14390 WP_001283427.1 2888464..2890296(-) (uvrC) [Escherichia coli strain EC31]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDESKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=585219 MYL27_RS14390 WP_001283427.1 2888464..2890296(-) (uvrC) [Escherichia coli strain EC31]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCCTTTATCTTCCT
GAGTGGCGATACCCATCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCTAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATATTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTGTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGTAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTGGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCATTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAATGCTTTGACATC
AGCCATACCATGGGGGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGACG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGAGAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAACTTGCGCAGGCGAAAAATGTTTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTAGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCACTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.056

99.508

0.379
  uvrC Streptococcus pneumoniae R6

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae D39

37.727

99.508

0.375