Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU525_RS03170 Genome accession   NZ_CP077920
Coordinates   641450..642019 (-) Length   189 a.a.
NCBI ID   WP_000872883.1    Uniprot ID   A0AAN1ZPK7
Organism   Staphylococcus aureus strain 277     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 636450..647019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU525_RS03130 (KU525_03115) - 636924..637532 (-) 609 WP_000020303.1 class I SAM-dependent methyltransferase -
  KU525_RS03135 (KU525_03120) rplL 637707..638075 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU525_RS03140 (KU525_03125) rplJ 638118..638618 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU525_RS03145 (KU525_03130) rplA 638890..639582 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU525_RS03150 (KU525_03135) rplK 639790..640212 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU525_RS03155 (KU525_03140) nusG 640393..640941 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU525_RS03160 (KU525_03145) secE 640954..641136 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU525_RS03165 (KU525_03150) rpmG 641192..641335 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU525_RS03170 (KU525_03155) sigH 641450..642019 (-) 570 WP_000872883.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU525_RS03175 (KU525_03160) - 642100..642624 (-) 525 WP_000664732.1 NYN domain-containing protein -
  KU525_RS03180 (KU525_03165) rlmB 642624..643370 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU525_RS03185 (KU525_03170) - 643378..643782 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  KU525_RS03190 (KU525_03175) cysS 643775..645175 (-) 1401 WP_000631962.1 cysteine--tRNA ligase -
  KU525_RS03195 (KU525_03180) cysE 645159..645806 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23070.93 Da        Isoelectric Point: 9.6015

>NTDB_id=585109 KU525_RS03170 WP_000872883.1 641450..642019(-) (sigH) [Staphylococcus aureus strain 277]
MKYDLTTQDSTIKRSNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=585109 KU525_RS03170 WP_000872883.1 641450..642019(-) (sigH) [Staphylococcus aureus strain 277]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAGCAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTTATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979