Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU509_RS08770 Genome accession   NZ_CP077917
Coordinates   1750901..1751470 (+) Length   189 a.a.
NCBI ID   WP_000872883.1    Uniprot ID   A0AAN1ZPK7
Organism   Staphylococcus aureus strain 280     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1745901..1756470
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU509_RS08745 (KU509_08795) cysE 1747114..1747761 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  KU509_RS08750 (KU509_08800) cysS 1747745..1749145 (+) 1401 WP_000631962.1 cysteine--tRNA ligase -
  KU509_RS08755 (KU509_08805) - 1749138..1749542 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  KU509_RS08760 (KU509_08810) rlmB 1749550..1750296 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU509_RS08765 (KU509_08815) - 1750296..1750820 (+) 525 WP_000664732.1 NYN domain-containing protein -
  KU509_RS08770 (KU509_08820) sigH 1750901..1751470 (+) 570 WP_000872883.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU509_RS08775 (KU509_08825) rpmG 1751585..1751728 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU509_RS08780 (KU509_08830) secE 1751784..1751966 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU509_RS08785 (KU509_08835) nusG 1751979..1752527 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU509_RS08790 (KU509_08840) rplK 1752708..1753130 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU509_RS08795 (KU509_08845) rplA 1753338..1754030 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU509_RS08800 (KU509_08850) rplJ 1754302..1754802 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU509_RS08805 (KU509_08855) rplL 1754845..1755213 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU509_RS08810 (KU509_08860) - 1755388..1755996 (+) 609 WP_000020303.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23070.93 Da        Isoelectric Point: 9.6015

>NTDB_id=585048 KU509_RS08770 WP_000872883.1 1750901..1751470(+) (sigH) [Staphylococcus aureus strain 280]
MKYDLTTQDSTIKRSNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=585048 KU509_RS08770 WP_000872883.1 1750901..1751470(+) (sigH) [Staphylococcus aureus strain 280]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAGCAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTTATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979