Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MYL26_RS06420 Genome accession   NZ_CP095823
Coordinates   1290124..1290780 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain STE15     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1285124..1295780
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL26_RS06390 (MYL26_06370) yecA 1286375..1287040 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  MYL26_RS06410 (MYL26_06390) pgsA 1287690..1288238 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYL26_RS06415 (MYL26_06395) uvrC 1288295..1290127 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  MYL26_RS06420 (MYL26_06400) letA 1290124..1290780 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYL26_RS06425 - 1290922..1291038 (+) 117 WP_001302039.1 hypothetical protein -
  MYL26_RS06430 (MYL26_06405) yecU 1291076..1291252 (+) 177 WP_000590344.1 protein YecU -
  MYL26_RS06435 (MYL26_06410) yecF 1291239..1291463 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYL26_RS06440 (MYL26_06415) sdiA 1291530..1292252 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  MYL26_RS06445 (MYL26_06420) tcyN 1292482..1293234 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYL26_RS06450 (MYL26_06425) tcyL 1293231..1293899 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  MYL26_RS06455 (MYL26_06430) dcyD 1293914..1294900 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=585035 MYL26_RS06420 WP_000611335.1 1290124..1290780(-) (letA) [Escherichia coli strain STE15]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=585035 MYL26_RS06420 WP_000611335.1 1290124..1290780(-) (letA) [Escherichia coli strain STE15]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486