Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KU502_RS11220 Genome accession   NZ_CP077916
Coordinates   2264834..2265706 (+) Length   290 a.a.
NCBI ID   WP_000593192.1    Uniprot ID   A0A140HKN1
Organism   Staphylococcus aureus strain 281     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2259834..2270706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU502_RS11200 (KU502_11235) sucC 2259948..2261114 (+) 1167 WP_001020799.1 ADP-forming succinate--CoA ligase subunit beta -
  KU502_RS11205 (KU502_11240) sucD 2261136..2262044 (+) 909 WP_000110251.1 succinate--CoA ligase subunit alpha -
  KU502_RS11210 (KU502_11245) - 2262271..2263389 (+) 1119 WP_001041673.1 LysM peptidoglycan-binding domain-containing protein -
  KU502_RS11215 (KU502_11250) fmhC 2263417..2264661 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  KU502_RS11220 (KU502_11255) dprA 2264834..2265706 (+) 873 WP_000593192.1 DNA-processing protein DprA Machinery gene
  KU502_RS11225 (KU502_11260) topA 2265880..2267955 (+) 2076 WP_072433106.1 type I DNA topoisomerase -
  KU502_RS11230 (KU502_11265) trmFO 2268111..2269418 (+) 1308 WP_000195259.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33564.99 Da        Isoelectric Point: 9.5094

>NTDB_id=585001 KU502_RS11220 WP_000593192.1 2264834..2265706(+) (dprA) [Staphylococcus aureus strain 281]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=585001 KU502_RS11220 WP_000593192.1 2264834..2265706(+) (dprA) [Staphylococcus aureus strain 281]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A140HKN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

100

100

1
  dprA Staphylococcus aureus N315

99.655

100

0.997