Detailed information NTG0584950

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: MYL38_RS06915
• Genome accession: NZ_CP095820
• Coordinates: 1446673..1447947 (+)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli strain Jnd12
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1441673..1452947

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MYL38_RS06895 (MYL38_06885)	yajG	1442836..1443414 (-)	579	WP_001295326.1	lipoprotein	-
MYL38_RS06900 (MYL38_06890)	bolA	1443719..1444036 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
MYL38_RS06905 (MYL38_06895)	tig	1444380..1445678 (+)	1299	WP_001198386.1	trigger factor	-
MYL38_RS06910 (MYL38_06900)	clpP	1445924..1446547 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
MYL38_RS06915 (MYL38_06905)	clpX	1446673..1447947 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
MYL38_RS06920 (MYL38_06910)	lon	1448135..1450489 (+)	2355	WP_001295325.1	endopeptidase La	-
MYL38_RS06925 (MYL38_06915)	hupB	1450698..1450970 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=584950 MYL38_RS06915 WP_000130305.1 1446673..1447947(+) (clpX) [Escherichia coli strain Jnd12]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=584950 MYL38_RS06915 WP_000130305.1 1446673..1447947(+) (clpX) [Escherichia coli strain Jnd12]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCACTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
TGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGACGTCCCGTTCACCATGGCCGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAGCTGTTGCAGAAGTGCGATTACGACGTACAGAAAGCGCAGCGCGGGATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCAGACAACCCGTCCATTACCCGAGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACGGTAGCTGCTGTTCCACCGCAAGGTGGGCGTAAACATCCGCAGCAGGAATTCTTGCAGGTTGATACC
TCTAAGATCCTGTTTATTTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCATCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTTATCCCTGAGTTTATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGACGTCGAAAAAGTGGTTATCGACGAA
TCGGTAATTGATGGTCAAAGCAAGCCGTTGCTGATTTATGGCAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533