Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   MYL34_RS10155 Genome accession   NZ_CP095806
Coordinates   2092403..2093059 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E371     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2087403..2098059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MYL34_RS10120 (MYL34_10065) dcyD 2088283..2089269 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  MYL34_RS10125 (MYL34_10070) tcyL 2089284..2089952 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  MYL34_RS10130 (MYL34_10075) tcyN 2089949..2090701 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  MYL34_RS10135 (MYL34_10080) sdiA 2090931..2091653 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  MYL34_RS10140 (MYL34_10085) yecF 2091720..2091944 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  MYL34_RS10145 (MYL34_10090) yecU 2091931..2092107 (-) 177 WP_000590344.1 protein YecU -
  MYL34_RS10150 - 2092145..2092261 (-) 117 WP_001302039.1 hypothetical protein -
  MYL34_RS10155 (MYL34_10095) letA 2092403..2093059 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  MYL34_RS10160 (MYL34_10100) uvrC 2093056..2094888 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  MYL34_RS10165 (MYL34_10105) pgsA 2094945..2095493 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  MYL34_RS10185 (MYL34_10125) yecA 2096143..2096808 (+) 666 WP_000847885.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=584792 MYL34_RS10155 WP_000611335.1 2092403..2093059(+) (letA) [Escherichia coli strain E371]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=584792 MYL34_RS10155 WP_000611335.1 2092403..2093059(+) (letA) [Escherichia coli strain E371]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486