Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   KU542_RS05290 Genome accession   NZ_CP077893
Coordinates   1002455..1003141 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 332     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 997455..1008141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU542_RS05255 (KU542_05260) yqeH 997982..999082 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  KU542_RS05260 (KU542_05265) aroE 999096..999902 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  KU542_RS05265 (KU542_05270) yhbY 999906..1000196 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  KU542_RS05270 (KU542_05275) nadD 1000199..1000768 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  KU542_RS05275 (KU542_05280) yqeK 1000758..1001342 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  KU542_RS05280 (KU542_05285) rsfS 1001343..1001696 (+) 354 WP_001088022.1 ribosome silencing factor -
  KU542_RS05285 (KU542_05290) - 1001699..1002415 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  KU542_RS05290 (KU542_05295) comEA 1002455..1003141 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  KU542_RS05295 (KU542_05300) - 1003233..1003694 (+) 462 WP_000439693.1 ComE operon protein 2 -
  KU542_RS05300 (KU542_05305) comEC 1003699..1005900 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  KU542_RS05305 (KU542_05310) holA 1005957..1006931 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  KU542_RS05310 (KU542_05315) rpsT 1006976..1007227 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=584651 KU542_RS05290 WP_001792568.1 1002455..1003141(+) (comEA) [Staphylococcus aureus strain 332]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=584651 KU542_RS05290 WP_001792568.1 1002455..1003141(+) (comEA) [Staphylococcus aureus strain 332]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969