Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU497_RS10350 Genome accession   NZ_CP077880
Coordinates   2020124..2020693 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 356     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2015124..2025693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU497_RS10310 (KU497_10285) - 2015598..2016206 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  KU497_RS10315 (KU497_10290) rplL 2016381..2016749 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU497_RS10320 (KU497_10295) rplJ 2016792..2017292 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU497_RS10325 (KU497_10300) rplA 2017564..2018256 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU497_RS10330 (KU497_10305) rplK 2018464..2018886 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU497_RS10335 (KU497_10310) nusG 2019067..2019615 (-) 549 WP_050956556.1 transcription termination/antitermination protein NusG -
  KU497_RS10340 (KU497_10315) secE 2019628..2019810 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU497_RS10345 (KU497_10320) rpmG 2019866..2020009 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU497_RS10350 (KU497_10325) sigH 2020124..2020693 (-) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU497_RS10355 (KU497_10330) - 2020774..2021298 (-) 525 WP_000664738.1 NYN domain-containing protein -
  KU497_RS10360 (KU497_10335) rlmB 2021298..2022044 (-) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU497_RS10365 (KU497_10340) - 2022052..2022456 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  KU497_RS10370 (KU497_10345) cysS 2022449..2023849 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  KU497_RS10375 (KU497_10350) cysE 2023833..2024480 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=584502 KU497_RS10350 WP_000872873.1 2020124..2020693(-) (sigH) [Staphylococcus aureus strain 356]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=584502 KU497_RS10350 WP_000872873.1 2020124..2020693(-) (sigH) [Staphylococcus aureus strain 356]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984