Detailed information
Bioinformatically predicted
Overview
| Name | comEA | Type | Machinery gene |
| Locus tag | KU500_RS00150 | Genome accession | NZ_CP077867 |
| Coordinates | 27484..28170 (+) | Length | 228 a.a. |
| NCBI ID | WP_078055782.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain 367 | ||
| Function | dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1..31960 | 27484..28170 | within | 0 |
Gene organization within MGE regions
Location: 1..31960
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KU500_RS00005 (KU500_00005) | - | 1..4530 (+) | 4530 | WP_001795393.1 | phage tail tape measure protein | - |
| KU500_RS00010 (KU500_00010) | - | 4527..6011 (+) | 1485 | WP_000567408.1 | phage distal tail protein | - |
| KU500_RS00015 (KU500_00015) | - | 6027..9812 (+) | 3786 | WP_000582158.1 | phage tail spike protein | - |
| KU500_RS00020 (KU500_00020) | - | 9802..9954 (+) | 153 | WP_001153681.1 | hypothetical protein | - |
| KU500_RS00025 (KU500_00025) | - | 10001..10288 (+) | 288 | WP_094659775.1 | hypothetical protein | - |
| KU500_RS00030 (KU500_00030) | - | 10346..10642 (+) | 297 | WP_000539688.1 | DUF2951 domain-containing protein | - |
| KU500_RS00035 (KU500_00035) | pepG1 | 10834..10968 (+) | 135 | WP_000226108.1 | type I toxin-antitoxin system toxin PepG1 | - |
| KU500_RS00040 (KU500_00040) | - | 11021..11128 (-) | 108 | WP_001791821.1 | hypothetical protein | - |
| KU500_RS00045 (KU500_00045) | - | 11180..11434 (+) | 255 | WP_000611512.1 | phage holin | - |
| KU500_RS00050 (KU500_00050) | - | 11446..12201 (+) | 756 | WP_000861038.1 | CHAP domain-containing protein | - |
| KU500_RS00055 (KU500_00055) | sak | 12392..12883 (+) | 492 | WP_000919350.1 | staphylokinase | - |
| KU500_RS00060 (KU500_00060) | - | 13530..13868 (+) | 339 | Protein_11 | SH3 domain-containing protein | - |
| KU500_RS00065 (KU500_00065) | scn | 14378..14728 (+) | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
| KU500_RS00070 (KU500_00070) | - | 14781..15041 (-) | 261 | WP_001791826.1 | hypothetical protein | - |
| KU500_RS13770 | - | 15020..15328 (-) | 309 | WP_001789576.1 | hypothetical protein | - |
| KU500_RS00075 (KU500_00075) | - | 15352..15531 (-) | 180 | WP_000669791.1 | hypothetical protein | - |
| KU500_RS00080 (KU500_00080) | - | 15937..17166 (+) | 1230 | WP_000533238.1 | NRAMP family divalent metal transporter | - |
| KU500_RS00085 (KU500_00085) | - | 17454..18674 (+) | 1221 | WP_225805746.1 | Fic family protein | - |
| KU500_RS00090 (KU500_00090) | - | 19498..20250 (+) | 753 | WP_001823975.1 | exotoxin | - |
| KU500_RS00095 (KU500_00095) | tnpA | 20442..20927 (-) | 486 | WP_000093395.1 | IS200/IS605 family transposase | - |
| KU500_RS00100 (KU500_00100) | - | 21196..21465 (-) | 270 | WP_000829750.1 | hypothetical protein | - |
| KU500_RS00105 (KU500_00105) | mtnN | 21777..22463 (+) | 687 | WP_000579267.1 | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | - |
| KU500_RS00110 (KU500_00110) | - | 22483..23010 (+) | 528 | WP_000524902.1 | YqeG family HAD IIIA-type phosphatase | - |
| KU500_RS00115 (KU500_00115) | yqeH | 23011..24111 (+) | 1101 | WP_001280141.1 | ribosome biogenesis GTPase YqeH | - |
| KU500_RS00120 (KU500_00120) | aroE | 24125..24931 (+) | 807 | WP_000666767.1 | shikimate dehydrogenase | - |
| KU500_RS00125 (KU500_00125) | yhbY | 24935..25225 (+) | 291 | WP_000955233.1 | ribosome assembly RNA-binding protein YhbY | - |
| KU500_RS00130 (KU500_00130) | nadD | 25228..25797 (+) | 570 | WP_000725167.1 | nicotinate (nicotinamide) nucleotide adenylyltransferase | - |
| KU500_RS00135 (KU500_00135) | yqeK | 25787..26371 (+) | 585 | WP_001017838.1 | bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK | - |
| KU500_RS00140 (KU500_00140) | rsfS | 26372..26725 (+) | 354 | WP_001088020.1 | ribosome silencing factor | - |
| KU500_RS00145 (KU500_00145) | - | 26728..27444 (+) | 717 | WP_000942456.1 | class I SAM-dependent DNA methyltransferase | - |
| KU500_RS00150 (KU500_00150) | comEA | 27484..28170 (+) | 687 | WP_078055782.1 | ComEA family DNA-binding protein | Machinery gene |
| KU500_RS00155 (KU500_00155) | - | 28262..28723 (+) | 462 | WP_000439693.1 | ComE operon protein 2 | - |
| KU500_RS00160 (KU500_00160) | comEC | 28728..30929 (+) | 2202 | WP_225805745.1 | DNA internalization-related competence protein ComEC/Rec2 | Machinery gene |
| KU500_RS00165 (KU500_00165) | holA | 30986..31960 (+) | 975 | WP_001282570.1 | DNA polymerase III subunit delta | - |
Sequence
Protein
Download Length: 228 a.a. Molecular weight: 25761.45 Da Isoelectric Point: 9.6753
>NTDB_id=584214 KU500_RS00150 WP_078055782.1 27484..28170(+) (comEA) [Staphylococcus aureus strain 367]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT
Nucleotide
Download Length: 687 bp
>NTDB_id=584214 KU500_RS00150 WP_078055782.1 27484..28170(+) (comEA) [Staphylococcus aureus strain 367]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCTAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTGCTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
GAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCTAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTGCTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
GAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comEA | Staphylococcus aureus MW2 |
98.678 |
99.561 |
0.982 |
| comEA | Staphylococcus aureus N315 |
98.678 |
99.561 |
0.982 |